Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster

By Hugh M. Robertson, Coral G. Warr, John R. Carlson. Proceedings of the National Academy of Sciences of the United States of America, 2003

805 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Insect Science

View Paper: https://www.semanticscholar.org/paper/f60ebf5f1ea387f5bf9c0902e9c5b6dab2bf3524

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Citations in the corpus

An alignment confidence score capturing robustness to guide tree uncertainty. (2010, methodology): “We applied the GUIDANCE method, using both MAFFT (Katoh et al. 2005) and ClustalW (Thompson et al. 1994), to an exemplary protein data set consisting of 130 homologous chemoreceptors from Drosophila melanogaster (Robertson et al. 2003).”
The evolution of animal chemosensory receptor gene repertoires: roles of chance and necessity (2008, background): “Insect OR and GR genes are distantly related and constitute a large superfamily of insect CR gene”
Olfactory representations by Drosophila mushroom body neurons. (2008, background): “In Drosophila, there are only ~60 different types of sensory neurons (OSNs), many of which have well characterized odor response properties (Clyne et al. 1999; Gao and Chess 1999; Hallem and Carlson 2006; Robertson et al. 2003; Vosshall et al. 1999; Vosshall and Stocker 2007).”
The molecular basis of odor coding in the Drosophila antenna. (2004, result): “Thus, our results demonstrate a critical in sequence (Robertson et al., 2003).”
Molecular architecture of smell and taste in Drosophila. (2007, background): “Robertson et al. (2003) argue that the absence of large clusters of related ORs suggests a very ancient origin of the gene family.”
Molecular, anatomical, and functional organization of the Drosophila olfactory system. (2005, neutral): “Adult Odorant Receptors The 60 Or genes of Drosophila are predicted to encode a total of 62 odorant receptors, from transcripts originating from 62 distinct Or promoters [4, 8–10].”
Evolution of insect olfaction. (2011, positive): “The insect ORs and the related gustatory receptors (GRs, Clyne et al., 2000; Scott et al., 2001) together form an arthropod-specific chemoreceptor superfamily, in which the ORs constitute a single highly expanded branch (Robertson et al., 2003).”
Complementary Function and Integrated Wiring of the Evolutionarily Distinct Drosophila Olfactory Subsystems (2011, background): “One possible driving force for the evolution of this second family of olfactory receptors is the evolution of terrestrial insects from aquatic arthropod ancestors 400 – 450 million years ago (Robertson et al., 2003; Engel and Grimaldi, 2004).”
Non-Canonical Odor Coding in the Mosquito (2020, background): “This holds true in Drosophila melanogaster flies (~60 receptors/~55 glomeruli) (Benton et al., 2009; Laissue et al., 1999; Robertson et al., 2003), the honey bee Apis mellifera (~180 receptors/~160 glomeruli) (Flanagan and Mercer, 1989; Robertson et al.”
Are bigger brains better? (2009, background): “The common fruit fly has 43 glomeruli within an antennal lobe whilst honeybees have w160 [7,45].”
Olfaction: diverse species, conserved principles. (2005, neutral): “…Niimura and Nei, 2003; (2) Gilad et al., 2005; (3) Gilad et al., 2004; (4) Young et al., 2003; (5) Rat Genome Sequencing Project Consortium, 2004; (6) Quignon et al., 2003; (7) Freitag et al., 1998; (8) Niimura and Nei, 2005; (9) Robertson et al., 2003; (10) Hill et al., 2002; (11) Robertson, 2001.”
Atypical Membrane Topology and Heteromeric Function of Drosophila Odorant Receptors In Vivo (2006, background): “Unexpectedly, unlike all known vertebrate and nematode chemosensory receptors, we find that Drosophila ORs and OR83b adopt a novel membrane topology with their N-termini and the most conserved loops in the cytoplasm.”