Polo-like kinases and the orchestration of cell division

By F. Barr, Herman H. W. Silljé, Erich A. Nigg. Nature reviews. Molecular cell biology, 2004

1,155 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f5caed34db5087a64067e9da3f6a64d604f390b4

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In Cell Biology

1. K. Strebhardt
2. Juergen A. Knoblich
3. David Glover
4. A. Ullrich
5. Ji Luo
6. Stephen J. Elledge

In Molecular Biology

1. K. Strebhardt
2. Juergen A. Knoblich
3. François Balloux
4. A. Ullrich
5. Stephen J. Elledge
6. Ji Luo

Citations in the corpus

• SAK/PLK4 is required for centriole duplication and flagella development. (2005, background): “Whereas much is now known about the mitotic functions of the founder member of the family, Drosophila Polo, and its related mammalian counterparts (Plk1–3) [1, 3, 4], the precise mitotic roles of SAK remain obscure.”
• Forkhead Box M1 Regulates the Transcriptional Network of Genes Essential for Mitotic Progression and Genes Encoding the SCF (Skp2-Cks1) Ubiquitin Ligase (2005, background): “Loss of Aurora B kinase and PLK1 activity causes chromosome alignment defects, because these kinases are critical for bipolar spindle microtubule attachment to each of the sister chromatid kinetochores and inhibit chromosome segregation because they phosphorylate and dissociate the cohesin protein c”
• Targeting polo-like kinase 1 for cancer therapy (2006, background): “The biology of PLK1 As the biological roles of the PLKs have been reviewed recentl”
• Chromosomal passengers: conducting cell division (2007, neutral): “CDK activation is complex, but is triggered in part by kinases of the Polo family , in particular Polo-like kinase-1 ( PLK1 ) in vertebrate”
• Mechanisms of asymmetric stem cell division. (2008, background): “Whereas Cdc2 is essential for mitosis in general, the kinases Aurora A, Aurora B, and Polo are only required for a subset of mitotic events (Meraldi et al., 2004; Barr et al., 2004).”
• The Polo kinase Plk4 functions in centriole duplication (2005, neutral): “Taken together, the above results demonstrate that cells depleted of Plk4 undergo a step-wise (4;2;1) loss of centrioles with continued passage through the cell cycle, indicating that Plk4 is indispensible for centriole duplication.”