Silver nanoparticles: synthesis, properties, toxicology, applications and perspectives

By Q. Tran, Van Quy Nguyen, Anh-Tuan Le. 2013

957 citations recorded by the source corpus.

In recent years the outbreak of re-emerging and emerging infectious diseases has been a significant burden on global economies and public health. The growth of population and urbanization along with poor water supply and environmental hygiene are the main reasons for the increase in outbreak of infectious pathogens. Transmission of infectious pathogens to the community has caused outbreaks of diseases such as influenza (A/H5N1), diarrhea (Escherichia coli), cholera (Vibrio cholera), etc throughout the world. The comprehensive treatments of environments containing infectious pathogens using advanced disinfectant nanomaterials have been proposed for prevention of the outbreaks. Among these nanomaterials, silver nanoparticles (Ag-NPs) with unique properties of high antimicrobial activity have attracted much interest from scientists and technologists to develop nanosilver-based disinfectant products. This article aims to review the synthesis routes and antimicrobial effects of Ag-NPs against various pathogens including bacteria, fungi and virus. Toxicology considerations of Ag-NPs to humans and ecology are discussed in detail. Some current applications of Ag-NPs in water-, air- and surface- disinfection are described. Finally, future prospects of Ag-NPs for treatment and prevention of currently emerging infections are discussed.

Subfields: Electronic, Optical and Magnetic Materials, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/f36225d4bbf26e4438142172aa6245102871ade1

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In Electronic, Optical and Magnetic Materials

In Materials Chemistry

Citations in the corpus

A review on green synthesis of silver nanoparticles and their applications (2017, background): “…non-aqueous solutions are used for the reduction of Ag ions, for example, poly-ethylene glycol block copolymers, sodium citrate, Tollen’s reagent, Ascorbate, essential hydrogen, N,N-dimethyl formamide (DMF), and sodium borohydride (NaBH4) (Tran and Le 2013; Guzm an et al. 2009; Chou and Ren 2000).”
A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives (2017, neutral): “Implementation of AgNPs in different sectors such as medical, biological, chemical, and electronical make them potential agents for inducing adverse human health effect, especially cardiovascular, central nervous system, malfunction, neurotoxicity, or immunotoxicity [133,134].”
Silver nanoparticles: synthesis, properties, and therapeutic applications (2014, background): “Therapeutic applications of AgNPs The function of AgNPs as antibacterial and antifungal agents has been well documented [54,55] and is not discussed here.”
Silver nanoparticles: various methods of synthesis, size affecting factors and their potential applications–a review (2020, background): “The two major steps of growth and nucleation occurred during the preparation of colloidal solutions (Tran et al. 2013).”
Silver Nanoparticles and Their Antibacterial Applications (2021, methodology): “Bottom-up methods include chemical and biological techniques applied to synthesize nanoparticles [1,12].”
A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: A green expertise (2015, neutral): “Different organic and inorganic reducing agents, such as sodium borohydride (NaBH4), sodium citrate, ascorbate, elemental hydrogen, Tollen’s reagent, N,N-dimethyl formamide (DMF) and poly (ethylene glycol) block copolymers are used for reduction of silver ions (Ag) in aqueous or non-aqueous solution”
Plant-Extract-Assisted Green Synthesis of Silver Nanoparticles Using Origanum vulgare L. Extract and Their Microbicidal Activities (2018, background): “Besides this, considering the potential of AgNPs for biological applications, the development of simple and environmentally benign approaches for their preparation using nontoxic reagents and solvents under ambient conditions is highly desirable [26,27].”
Green Synthesis of Silver Nanoparticles: A Review (2016, background): “The AgNPs are being used to treat many environmental concerns like; air disinfection, water disinfection, ground water and biological water disinfection and surface disinfection [153].”
Green nanobiotechnology: factors affecting synthesis and characterization techniques (2014, background): “The rate of reduction of metal ions using biological agents has been found to be much faster at ambient pressure conditions [28].”
Mechanistic Basis of Antimicrobial Actions of Silver Nanoparticles (2016, background): “Other biomedical applications of AgNPs include impregnation of catheters and cardiovascular and bone implants with AgNPs for inhibiting biofilm formation and minimizing the chances of pathogenic growth (Tran et al., 2013).”