Endoreplication cell cycles: more for less.
By Bruce Edgar, T. Orr-Weaver. 2001
862 citations recorded by the source corpus.
Subfields: Cell Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/f2703db72e9088232c0b1b3222f151b2f4e2bf92
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In Cell Biology
In Plant Science
Citations in the corpus
- How cells coordinate growth and division. (2004, background): “Ploidy increases are apparently required to prevent genomic DNA from becoming limiting for cell growth [19].”
- Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development (2003, background): “Trophoblast giant cells are polyploid cells that arise from endoreplication, a process often associated with highly metabolically active cells (Edgar and Orr-Weaver, 2001).”
- REVIEW: PART OF A SPECIAL ISSUE ON THE PLANT CELL CYCLE Elucidating the functional role of endoreduplication in tomato fruit development (2011, background): “Endoreduplication often occurs during the differentiation of cells that are highly specialized in their morphology and its blockage by mutation results in developmental abnormalities (Kondorosi et al., 2000, 2005; Edgar and Orr-Weaver, 2001).”
- Genetic and epigenetic mechanisms for gene expression and phenotypic variation in plant polyploids. (2007, background): “Except for endopolyploidy (a diploid individual with cells containing more than 2 C amount of DNA in their nuclei) in some cell types (37), aneuploid and polyploid cells in animals and humans are often associated with malignant cell proliferation or carcinogenesis (136).”
- Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditions. (2002, background): “This cycle employs successive rounds of DNA synthesis without intervening mitoses, generating polyploid cells (Edgar and Orr-Weaver, 2001).”