Pluronic block copolymers as novel polymer therapeutics for drug and gene delivery.

By A. Kabanov, E. Batrakova, V. Alakhov. Journal of Controlled Release, 2002

1,317 citations recorded by the source corpus.

Subfields: Biomaterials, Molecular Biology, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/f1f532a8f82a889188e8285fe1fea0ccff6391ac

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Citations in the corpus

Nanoparticles in Medicine: Therapeutic Applications and Developments (2008, background): “Poly(D,L-lactic acid), poly(D,L-glycolic acid), poly(e-caprolactone), and their copolymers at various molar ratios diblocked or multiblocked with poly(ethylene glycol) are the most commonly used biodegradable polymers to form micelles for drug delivery and controlled release, and have been extensive”
Polymeric Micelles in Anticancer Therapy: Targeting, Imaging and Triggered Release (2010, background): “Generally, the more hydrophobic and the higher the molecular weight, the lower the CMC (14, 19 ).”
Strategies to Address Low Drug Solubility in Discovery and Development (2013, background): “…Synperonics) comprise a hydrophobic poly (propylene oxide) central segment flanked on either side by more hydrophilic ethylene oxide blocks (Kabanov et al., 2002) and are a class of nonionic polymeric surfactants that have attained significant recent interest for drug solubilization and…”
Zinc Oxide Nanoparticles for Selective Destruction of Tumor Cells and Potential for Drug Delivery Applications (2010, background): “Pluronic block copolymers [123] Doxorubicin Various cancers Polymer--lipid hybrid nanoparticles [124] Doxorubicin Solid tumors Poly(lactic-co-glycolic acid)-block-poly(ethylene glycol) [125] Docetaxel Prostate cancers”
Block copolymer micelles: preparation, characterization and application in drug delivery. (2005, neutral): “copolymers of (poly(ethylene glycol)-b-poly(propylene oxide)-bpoly(ethylene glycol)) (PEG-b-PPO-b-PEG) [7].”
Micellar Nanocarriers: Pharmaceutical Perspectives (2006, background): “Drugs, such as diazepam and indomethacin (123,124), adriamicin (90,125Y127), anthracycline antibiotics (128), polynucleotides (129,130), and doxorubicin (131) were effectively solubilized by various polymeric micelles, including Pluronic (block co-polymers of PEG and polypropelene glycol) (52).”