Cdc42 regulates GSK-3β and adenomatous polyposis coli to control cell polarity

By Sandrine Étienne-Manneville, A. Hall. Nature, 2003

713 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f18f2dd693775be4843b4361b303853ba4b07b3f

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In Cell Biology

1. S. Heasman
2. A. Ridley
3. Manuel Théry
4. Eléonore Beurel
5. R. Jope

In Molecular Biology

1. Eléonore Beurel
2. S. Heasman
3. S. Grieco
4. A. Ridley
5. R. Jope

Citations in the corpus

• Mammalian Rho GTPases: new insights into their functions from in vivo studies (2008, background): “For example, CDC42 and the PAR complex (PAR6–PAR3–aPKC) have been proposed to mediate the capture and stabilization of microtubules at the front of the cell and to orientate the Golgi and microtubule-organizing centre (MTOC) during the establishment of migratory polarit”
• Glycogen Synthase Kinase-3 (GSK3): Inflammation, Diseases, and Therapeutics (2007, background): “This inhibition of GSK3 prevents it from phosphorylating adenomatous polyposis coli (APC) protein which allows APC to associate with the plus-ends of microtubules to establish cell polarity and control the direction of cell protrusion [28].”
• Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases (2014, background): “, 2004), cell polarity (Etienne-Manneville and Hall, 2003), and focal adhesions (Cai et al.”
• The extracellular matrix guides the orientation of the cell division axis (2005, background): “Elsewhere it has been found that membrane ruffles contain proteins that stabilize microtubules such as AP”