Mesenchymal stem cells and their potential as cardiac therapeutics.
By M. Pittenger, B. Martin. Circulation Research, 2004
1,463 citations recorded by the source corpus.
Subfields: Biomaterials, Genetics, Surgery
View Paper: https://www.semanticscholar.org/paper/efa0e617156959135d0b1a2a9e4265f225e419d8
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Citations in the corpus
- Evidence supporting paracrine hypothesis for Akt‐modified mesenchymal stem cell‐mediated cardiac protection and functional improvement (2006, background): “The low periimplantation viability of the injected cells may limit the capacity of this mechanism to result in meaningful cardiac regeneration ( 14 ).”
- Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs (2009, background): “Mesenchymal stem cells (MSCs), derived from adult bone marrow, have emerged as one of the most promising stem cell types for treating cardiovascular disease (10), and MSC is known to exert its therapeutic effects via secreted trophic factors (11–14).”
- Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma (2006, background): “Because of these properties, MSCs have considerable therapeutic potential in several disease processes, including cardiovascular disease (20), as well as in the treatment of human malignancies (21).”
- Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury. (2010, methodology): “Mesenchymal stem cells (MSCs) derived from adult bone marrow have emerged as one of the most promising stem cell types for treating cardiovascular disease (Pittenger and Martin, 2004).”
- Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium. (2008, background): “Among the stem cells that have been tested for cardiac repair, mesenchymal stem cells (MSCs) derived fromadult bonemarrow have emerged as one of the most promising stem cell types for treating cardiovascular disease (Pittenger and Martin, 2004).”