BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory?

By Yuan Lu, Kimberly M. Christian, B. Lu. Neurobiology of Learning and Memory, 2008

801 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/ef8ce1ecc6fd784a36bd69bccfbe9f63c78eaf14

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. B. Lu
2. Jan Born
3. A. Watt
4. Björn H. Rasch
5. Anita E. Autry
6. B. Hempstead
7. L. Monteggia
8. Michael E. Greenberg

In Developmental Neuroscience

1. B. Lu
2. B. Hempstead
3. Michael E. Greenberg
4. C. Duarte
5. Graciano Leal
6. Diogo Comprido
7. Niraj S. Desai
8. A. Watt

Citations in the corpus

• New insights in the biology of BDNF synthesis and release: implications in CNS function (2009, positive): “…are central to many facets of CNS function, with critical roles in cell differentiation, neuronal survival, migration, dendritic arborization, synaptogenesis, and activity-dependent forms of synaptic plasticity (Reichardt, 2006; Bramham, 2008; Cohen and Greenberg, 2008; Lu et al., 2008).”
• Frontiers in Synaptic Neuroscience Synaptic Neuroscience (positive): “Interestingly, BDNF is also implicated in LTP, where it is thought to be required for expression of the late, protein-dependent phase of LTP (Minichiello, 2009), or alternatively, synaptic tagging (Lu et al., 2008).”
• About sleep's role in memory. (2013, background): “The expression of BDNF and PKM- are further important signals not only supporting induction of LTP but in particular for mediating the emergence of late LTP (746, 850, 1020).”
• BDNF-induced local protein synthesis and synaptic plasticity. (2014, positive): “The neurotrophin brain-derived neurotrophic factor (BDNF) has been shown to play a key role asmediator of activity-induced LTP in the hippocampus as well as in other brain regions (Bramham and Messaoudi, 2005; Cowansage et al., 2010; Lu et al., 2008; Minichiello, 2009; Park and Poo, 2013; Santos et ”
• Immune modulation of learning, memory, neural plasticity and neurogenesis. (2011, background): “As described above (Section 1.4.3.3), BDNF has been implicated in hippocampal-dependent memory (Barnes and Thomas, 2008; Heldt et al., 2007), LTP (Lu et al., 2008) and neurogenesis (Li et al., 2008).”
• Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders (2012, background): “, 2004) and decreased learning and memory in behavioral paradigms (Lu et al., 2008).”