MicroRNA biogenesis and cancer.

By Richard I. Gregory, R. Shiekhattar. Cancer Research, 2005

742 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/dfac4bb9da954953c6caf974585333e1811d1fcd

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Citations in the corpus

Impaired microRNA processing enhances cellular transformation and tumorigenesis (2007, background): “Many of these target mRNA transcripts are involved in proliferation, differentiation and apoptosi”
MicroRNA: Biogenesis, Function and Role in Cancer (2010, background): “The most current processing model suggest that DGCR8 recognizes the primiRNA at the ssRNA-dsRNA junction and directs Drosha to a specific cleavage site ~11 base pairs (bp) from the junction on the stem where Drosha cuts to liberate a ~ 60-70 bp miRNA hairpin precursor (pre-miRNA) [78, 80, 81, 83, 86”
miRNAs, cancer, and stem cell division. (2005, background): “…last three years have demonstrated that there is altered expression of miRNA genes in several human malignancies, including chronic lymphocytic leukemia, pediatric Burkitt’s lymphoma, gastric cancer, lung cancer, and large cell lymphoma (reviewed in McManus, 2003 and Gregory and Shiekhattar, 2005).”
MicroRNA signature predicts survival and relapse in lung cancer. (2008, background): “With the advent of miRNA expression profiles, significant efforts have been made to correlate miRNA expressions with tumor prognosis (Calin and Croce, 2006a, 2006b; Cummins and Velculescu, 2006; Esquela-Kerscher and Slack, 2006; Garzon et al., 2006; Gregory and Shiekhattar, 2005).”
Identification of metastasis‐related microRNAs in hepatocellular carcinoma (2008, neutral): “064 2 9 ( 1) 1 ( 1) 0 CLIP stage 0 106 (44) 61 (47) 45 (41) 1 83 (34) 43 (33) 40 (36) 2 52 (22) 27 (21) 25 (23) 0.”
miRWalk - Database: Prediction of possible miRNA binding sites by "walking" the genes of three genomes (2011, background): “In the past couple of years, research groups demonstrated the involvement of miRNAs in complicated biological processes/pathways, including the control of developmental timing, haematopoietic cell differentiation, apoptosis, cell proliferation, organ development [10,11,46,47], as well as cancerogene”