Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles.

By L. O’Mahony, J. McCarthy, P. Kelly, G. Hurley, Fangyi Luo, Ker-Sang Chen, G. O'sullivan, B. Kiely, J. Collins, F. Shanahan and 1 more. Gastroenterology, 2005

1,458 citations recorded by the source corpus.

Subfields: Food Science, Gastroenterology, Pharmacy

View Paper: https://www.semanticscholar.org/paper/ee78f2e301d8468b5c3ee772b5e021984cf75520

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Food Science

1. Ted G. Dinan
2. J. Cryan
3. G. Clarke
4. K. Verbeke

In Gastroenterology

1. J. Cryan
2. Ted G. Dinan
3. G. Clarke
4. C. Stanton
5. B. Lacy
6. M. Simrén
7. S. Grenham
8. E. Quigley

In Pharmacy

1. J. Cryan
2. Ted G. Dinan
3. G. Clarke
4. C. Stanton
5. S. Grenham
6. E. Quigley
7. S. Mazmanian
8. T. Sampson

Citations in the corpus

• Efficacy of an Encapsulated Probiotic Bifidobacterium infantis 35624 in Women with Irritable Bowel Syndrome (2006, methodology): “infantis 35624 has been shown to be superior to Lactobacillus salivarius UCC4331 (21) in a head-to-head comparison in IBS, and the results presented here are superior to those achieved previously with other probiotic strains (20, 35–39) suggesting that this particular organism may possess unique pro”
• The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat. (2008, background): “Furthermore, in inflammatory disorders such as IBS, treatment with bifidobacteria normalises the imbalance that exists between pro-inflammatory and anti-inflammatory cytokines in this disorder (O’Mahony et al., 2005).”
• Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions (2010, background): “, who reported that secretion of cytokines from unstimulated, cultured PBMCs was shifted towards a decreased production of IL-10 and an increased production of IL-12”
• Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve (2011, background): “46. van der Kleij H, O’Mahony C, Shanahan F, O’Mahony L, Bienenstock J (2008) Protective effects of Lactobacillus reuteri and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve.”
• Dysbiosis of the gut microbiota in disease (2015, background): “free mice (78) and this hyper-response of the HPA axis was reversed by Bifidobacterium infantis (84).”