Breast cancer stem cells, cytokine networks, and the tumor microenvironment.

By H. Korkaya, Suling Liu, M. Wicha. Journal of Clinical Investigation, 2011

612 citations recorded by the source corpus.

Subfields: Cancer Research, Oncology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/7d051a180279c0da474e234266f49866bbe66a5e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Zena Werb
2. Lisa M. Coussens
3. D. Hanahan
4. V. Plaks
5. Niwen Kong
6. Rakesh K. Jain
7. Raghu Kalluri
8. J. Joyce

In Oncology

1. Zena Werb
2. Lisa M. Coussens
3. D. Hanahan
4. V. Plaks
5. Niwen Kong
6. E. Song
7. J. Slingerland
8. Pengfei Lu

In Psychiatry and Mental health

1. Niwen Kong
2. Zena Werb
3. V. Plaks
4. Lisa M. Coussens
5. D. Hanahan

Citations in the corpus

• Accessories to the crime: functions of cells recruited to the tumor microenvironment. (2012, positive): “…Psaila and Lyden, 2009), and (2) the myofibroblastic/MSC subtype of CAFs, likely also present in metastatic vascular stem cell niches (Kidd et al., 2009; Korkaya et al., 2011; Liu et al., 2011; Spaeth et al., 2008, 2009); similar niche-forming cells may also nurture CSCs inside primary tumors.”
• CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness. (2018, positive): “Like normal stem cells, the maintenance of CSC properties requires a supportive niche (Korkaya et al., 2011).”
• PREVALENCE, MECHANISMS, AND MANAGEMENT OF CANCER-RELATED COGNITIVE IMPAIRMENT (2014, background): “Cancer patients have increased levels of circulating cytokines (compared to healthy controls) (Korkaya et al., 2011; Rego et al., 2013), and infl ammation has been associated with chemotherapy treatment and cognitive dysfunction (Janelsins et al., 2012), supporting a role for dysregulated immune…”
• Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. (2014, background): “Many of these interactions between stromal cells and tumor cells may support the maintenance of cancer stem-like cells (i.e., tumorinitiating cells) analogously to how normal stem cells depend on a niche (Korkaya et al., 2011).”
• The Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells? (2015, positive): “Normal niches are comprised of fibroblastic cells, immune cells, endothelial and perivascular cells or their progenitors, extracellular matrix (ECM) components, and networks of cytokines and growth factors (Korkaya et al., 2011).”