Iron, brain ageing and neurodegenerative disorders

By L. Zecca, M. Youdim, P. Riederer, James R. Connor, R. Crichton. Nature Reviews Neuroscience, 2004

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Citations in the corpus

Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases (2015, background): “…sword Frontiers in Cellular Neuroscience | www.frontiersin.org 10 April 2015 | Volume 9 | Article 124 that may increase their vulnerability since iron may react with ROS produced from dopamine metabolism and promote the further generation of highly toxic radicals (Zecca et al., 2002, 2004).”
Oxidative stress and neurodegeneration: where are we now? (2006, background): “(iv) Iron is found throughout the brain (Burdo and Connor 2003; Zecca et al. 2004).”
Ageing and neuronal vulnerability (2006, background): “Ageing: setting the stage for a neurocatastrophe Cells in the nervous system are affected by, and respond to, ageing much as cells in other organ systems do, and so cells in the brain experience increased amounts of oxidative stres”
Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness (2006, background): “As well, several mutated genes have been linked to iron accumulation in the brain in aceruloplasminemia, Friedrich’s ataxia and other neurodegenerative conditions (Zecca et al., 2004; Mandel et al., 2005).”
An iron-export ferroxidase activity of β-amyloid protein precursor is inhibited by zinc in Alzheimer’s Disease (2010, neutral): “, 2002) and is a feature of several neurodegenerative disorders (Zecca et al., 2004).”
Oxidative stress in neurodegenerative diseases (2012, background): “[71] Zecca L, Youdim MB, Riederer P, et al.”