Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors

By J. Yamashita, H. Itoh, M. Hirashima, M. Ogawa, Satomi Nishikawa, Takami Yurugi, M. Naito, K. Nakao, Shin-ichi Nishikawa. Nature, 2000

1,432 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ecf5a9e327017e5b8f36545cfcd66989a8a67b51

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In Cell Biology

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Citations in the corpus

• Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? (2002, result): “Another study showed that treatment of CEPs that were isolated from EMBRYOID BODIES gave rise to differentiated endothelial cell”
• Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. (2005, methodology): “org Volume 115 Number 2 February 2005 To induce differentiation into SMC lineages, hBMSCs were replated at 1 × 105 cells per square centimeter in noncoated or fibronectin-coated plastic dishes in 1–2% DMEM or EBM-2 supplemented with PDGF-BB (50 ng/ml) (22).”
• Differential roles of vascular endothelial growth factor receptor-1 and receptor-2 in angiogenesis. (2006, background): “These cells form blood islands at yolk sac, and start hematopoiesis (Shalaby et al., 1995; Eichmann et al., 1997; Yamashita et al., 2000).”
• Bone tissue engineering: state of the art and future trends. (2004, positive): “The differentiation potential of these cells has been reported by several authors, in which cardiomyocytes [196], haematopoietic cells [197], endothelial cells [198,199], neurons [200,201], chondrocytes [202,203], adypocytes [204,205], hepatocytes [206,207] and pancreatic islets [208], were differen”
• Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration (2003, background): “EPCs from embryonic stem cells Mouse VEGFR2 + cells isolated from embryoid bodies can differentiate into endothelial and smooth muscle cell”
• Bone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications (2001, background): “Secondly, as recently shown, pericytes may arise directly from endothelial cells or their progenitors [51, 52 ].”
• Endothelial cells and VEGF in vascular development (2005, background): “During embryonic stem (ES) cell differentiation, isolated Flk1-positive progenitors can produce smooth-muscle-type cell”
• The role of pericytes in blood-vessel formation and maintenance. (2005, neutral): “2A) (Carmeliet, 2004; Yamashita et al., 2000).”