Bone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications

By P. Bianco, M. Riminucci, S. Gronthos, P. Robey. Stem Cells, 2001

2,018 citations recorded by the source corpus.

Subfields: Cancer Research, Genetics, Rheumatology

View Paper: https://www.semanticscholar.org/paper/d9e0803caefbf6f4919b49e11a05e47b62758279

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Antonio Giordano
2. P. Simmons
3. P. Robey
4. A. Caplan

In Genetics

1. Rocky S. Tuan
2. S. Shi
3. S. Gronthos
4. G. T. Huang
5. D. Baksh
6. L. Song
7. Fanxin Long
8. P. Robey

In Rheumatology

1. S. Shi
2. S. Gronthos
3. P. Robey

Citations in the corpus

• Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy (2004, background): “[30]) strongly suggest that MSCs and isolated MSC clones are heterogeneous with respect to their self- renewal capacity.”
• Bone regeneration strategies: engineered scaffolds, bioactive molecules and stem cells Current stage and future perspectives (2018, positive): “Since there is little extracellular matrix present in marrow, gentle mechanical disruption can readily dissociate stroma and hematopoietic cells from the bone marrow harvested into a single-cell suspension [138].”
• Fracture healing as a post‐natal developmental process: Molecular, spatial, and temporal aspects of its regulation (2003, background): “A wealth of data also exists demonstrating that marrow stromal cells within the trabecular space are capable of undergoing differentiation into not only osteoblasts but chondrocytes as well [Jaiswal et al., 1997; Bianco et al., 2001; Sekiya et al., 2002].”
• Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow (2003, background): “It has been suggested that that osteoprogenitors may be associated with the outer surfaces of the marrow vasculature (Bianco et al., 2001).”
• Small molecule functional groups for the controlled differentiation of human mesenchymal stem cells encapsulated in poly(ethylene glycol) hydrogels (2008, neutral): “dtd" [ ]> Interactions of cells and extracellular matrix (ECM) initiate signalling cascades involved in critical cell functions, such as regeneratio”