Demethylation of H3K27 Regulates Polycomb Recruitment and H2A Ubiquitination
By Min Gyu Lee, R. Villa, P. Trojer, Jessica A. Norman, Kai-ping Yan, D. Reinberg, L. Di Croce, R. Shiekhattar. Science, 2007
785 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/ebcec7c507545a36d2d1bb64ebb032056e8368d5
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In Molecular Biology
- Luciano Di Croce
- D. Reinberg
- A. Shilatifard
- B. Schuettengruber
- H. Bourbon
- P. Voigt
- Wee-Wei Tee
- Dirk Schübeler
Citations in the corpus
- The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis (2012, background): “Surprisingly, UTX was identified to co-purify with the MLL3/MLL4 complexes (64, 65, 69, 78) and to function during retinoic acid signaling events (78).”
- Genome Regulation by Polycomb and Trithorax: 70 Years and Counting. (2017, positive): “…demethylase (KDM) specific for H3K4me3 (little imaginal discs [Lid]) has been classified as a TrxG protein in Drosophila (Eissenberg et al., 2007; Lee et al., 2007b; Secombe et al., 2007), and its mammalian homolog, JARID1d, associates with PCL proteins regulating transcriptional initiation…”
- CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing (2009, background): “UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.”
- Transcriptional regulation by Polycomb group proteins (2013, background): “; and from the Novo Nordisk Foundation, the Danish Cancer Society and the Danish Council for Strategic Research (12-110503) to K.”
- Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease. (2008, background): “2007), and lately, the UTX/JMJD3 group, capable of demethylating H3K27me3/me2/me1 (Agger et al. 2007; De Santa et al. 2007; Jepsen et al. 2007; Lan et al. 2007a; Lee et al. 2007b).”
- Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. (2008, background): “However, while DNA methylation is considered a stable epigenetic silencer, Polycomb-mediated repression is reversible, as targets such as Hox genes are activated in a cell-type-specific manner (Agger et al., 2007; Bracken et al., 2006; Lan et al., 2007; Lee et al., 2007; Mikkelsen et al., 2007).”