Rigidity Sensing at the Leading Edge through αvβ3 Integrins and RPTPα

By Guoying Jiang, A. Huang, Yunfei Cai, M. Tanase, M. Sheetz. 2006

232 citations recorded by the source corpus.

Subfields: Atomic and Molecular Physics, and Optics, Cell Biology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/eaf94f7a1f3f16ff1832ff8c528f5b1b22746328

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Atomic and Molecular Physics, and Optics

1. Clare M. Waterman
2. Viola Vogel
3. Sergey V Plotnikov
4. M. Sheetz
5. B. Hinz

In Cell Biology

1. Clare M. Waterman
2. Viola Vogel
3. E. Danen
4. M. Sheetz
5. S. Huveneers
6. Ulrich S. Schwarz
7. B. Hinz
8. Subra Suresh

In Immunology and Allergy

1. Clare M. Waterman
2. E. Danen
3. M. Sheetz
4. S. Huveneers

Citations in the corpus

• Adhesion signaling – crosstalk between integrins, Src and Rho (2009, background): “For example, integrin αvβ3 might activate Src in response to increased fibronectin rigidity during tumorigenesis (Huveneers et al., 2007; Jiang et al., 2006), and it has been reported that cells respond to mechanical tension through the activation of integrins, Rho-GTPases and SFKs (Matthews et…”
• Force Fluctuations within Focal Adhesions Mediate ECM-Rigidity Sensing to Guide Directed Cell Migration (2012, background): “…processes , including regulating proliferation and differentiation (Engler et al., 2006; Ingber and Folkman, 1989), growth of focal adhesions (FAs), contractility, spreading, and cell polarization (Pelham and Wang, 1997; Riveline et al., 2001; Jiang et al., 2006; Prager-Khoutorsky et al., 2011).”
• Local force and geometry sensing regulate cell functions (2006, background): “Recent studies indicate that the loading rate of the force onto the cell can be crucia”