Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion.

By H. Hohmeier, H. Mulder, Guoxun Chen, Rosemarie Henkel-Rieger, M. Prentki, C. B. Newgard. Diabetes, 2000

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Measuring ER stress and the unfolded protein response using mammalian tissue culture system (2011, background): “The mouse b cell line, MIN6, and the rat b cell lines, INS-1 and INS-1 832/13, are often used to study ER stress and the UPR in the context of the b cell (Asfari et al., 1992; Hohmeier et al., 2000; Miyazaki et al., 1990).”
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy (2008, methodology): “The INS1 cells used here were derived from rat insulinoma (pancreatic tumor b-cells) and are characterized by a linear relationship between insulin secretion and glucose concentration within a range of 2–10mM (Hohmeier et al, 2000).”
The Pleiotropic Actions of Adiponectin are Initiated via Receptor-Mediated Activation of Ceramidase Activity (2010, methodology): “The rat insulinoma cell line INS-1 832/13 was cultured as previously describe”
Triggering and amplifying pathways of regulation of insulin secretion by glucose. (2000, methodology): “Using the same paradigm of K-induced depolarization in the presence of diazoxide, many laboratories have confirmed that glucose can increase insulin secretion independently of its action on KATP channels in rodent islets (45–49), human islets (50), perfused rat pancreas (51), and insulin-secreting c”