Antibiotics and Antibiotic Resistance Genes in Natural Environments

By J. Martínez. Science, 2008

1,744 citations recorded by the source corpus.

Subfields: Immunology, Molecular Medicine, Pollution

View Paper: https://www.semanticscholar.org/paper/eabea3862df7c58a4fc1cffece83b541c249a1ee

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Citations in the corpus

Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer (2016, background): “…antibiotics have existed for billions of years (Barlow and Hall, 2002; Hall and Barlow, 2004; Bhullar et al., 2012; Wright and Poinar, 2012), providing a selective benefit for the producing strains by inhibiting or eliminating other bacteria competing for resources (Martinez, 2008; Aminov, 2009).”
Adsorption of two antibiotics on biochar prepared in air-containing atmosphere: Influence of biochar porosity and molecular size of antibiotics (2019, background): “The frequent occurrence of water contamination by antibiotics leads to the increasing concern on their potential adverse impacts on human health and ecosystems [23], and biochar and biomass-derived carbons”
Integrons: Past, Present, and Future (2014, background): “Consequently, simultaneous pollution with integrons and selective agents has the potential impose new selective forces on environmental microorganisms (244).”
The Logic of Chance: The Nature and Origin of Biological Evolution (2011, background): “Perhaps the most straightforward and familiar case in point is the evolution of antibiotic resistance (Martinez, 2008; Wright, 2007).”
Co-selection of antibiotic and heavy metal resistance in freshwater bacteria (2016, background): “Nonetheless, the crucial importance of the environment (particularly waters and sediments), and of natural non-pathogenic bacteria as a long-term reservoir of ARGs becomes more and more evident (Martinez, 2008; Taylor et al., 2011).”
In-feed antibiotic effects on the swine intestinal microbiome (2012, background): “A central concern of increased abundance of antibiotic resistance is the transfer of resistance to pathogens (13).”
A Brief History of the Antibiotic Era: Lessons Learned and Challenges for the Future (2010, background): “…interaction has been broadening beyond the bullet-target model to reflect the complexity of these interactions (Davies et al., 2006; Fajardo and Martínez, 2008; Aminov, 2009; Lee et al., 2010). resistAnce problem complexity The current state in the field of antimicrobials, resistance, and…”
Contamination of surface, ground, and drinking water from pharmaceutical production (2009, background): “Environmental bacteria constitute a potential recruitment pool for resistance factors that, through horizontal gene transfer, may end up in human pathogens [17,18], rendering current treatment regimens useless.”
Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation. (2016, background): “The environment has repeatedly been identified as a source for resistance genes to pathogens (D'Costa et al., 2006, 2011; Finley et al., 2013; Martinez, 2008; Pruden et al., 2013; Wright, 2010), however, it is unclear to what extent antibiotics in the environment contribute to this development.”