Reactive Oxygen Species as Intracellular Messengers During Cell Growth and Differentiation

By H. Sauer, M. Wartenberg, J. Hescheler. Cellular Physiology and Biochemistry, 2001

1,120 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/ea94e97e9fbd2943ba734688bbd68abc7fe4bd00

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Citations in the corpus

Vascular NAD(P)H oxidases: specific features, expression, and regulation. (2003, neutral): “The role of ROS in signaling has been reviewed extensively (47, 49, 50, 52, 63, 64, 66, 87, 99, 138, 162, 187, 190, 191, 195, 197, 217, 222).”
Reactive oxygen species in vascular biology: implications in hypertension (2004, positive): “However, there is now convincing evidence that ROS are not only toxic consequences of cellular metabolism but also essential participants in cell signaling and regulation (Griendling et al. 2000a; Sauer et al. 2001; Reth 2002; Chiarugi and Cirri 2003).”
Stress response, cell death and signalling: the many faces of reactive oxygen species (2003, background): “But although the concept of redox regulation is an old one in enzymology, there is a new and growing awareness that ROS and redox regulation are central to cell signalling and to both transcriptional and post-transcriptional regulation (Sauer et al. 2001, Droge 2002, Ermak and Davies 2002).”
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals (2007, background): “O 2 −• is also produced by metabolic oxidases, including NADPH oxidase and xanthine oxidas”
Mitochondrial electron transport chain: Oxidative phosphorylation, oxidant production, and methods of measurement (2020, background): “phosphorylation signaling [26,27], and cell growth and differentiation [28,29].”
Calcium, ATP, and ROS: a mitochondrial love-hate triangle. (2004, background): “Several recent studies have shown that perturbations in mitochondrial ROS generation can affect diverse redox signaling pathways such as the cell cycle (167), cell proliferation (98), apoptosis (108), metalloproteinase function (155), oxygen sensing (30), protein kinases (154, 155), phosphatases (15”
Myeloid-derived-suppressor cells as regulators of the immune system (2009, positive): “In addition, several known tumour-derived factors, such as TGFβ, IL-3, IL-6, IL-10, platelet-derived growth factor and GM-CSF, can induce the production of ROS by MDSCs (for a review, see Ref”
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. (2006, background): “ROS in physiology and oxidative stress ROS are produced during normal physiological cellular events, and are involved in various biological processes, including regulation of proliferation, activation of gene expression and cellular response to cytokines [66–68].”