Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats.

By K. Maiti, K. Mukherjee, Arunava Gantait, B. P. Saha, P. Mukherjee. International journal of pharmaceutics, 2007

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Design of Curcumin Loaded PLGA Nanoparticles Formulation with Enhanced Cellular Uptake, and Increased Bioactivity in vitro and Superior Bioavailability in vivo (2009, neutral): “Curcumin has been conjugated with numerous carriers including phospholipids [18], cyclodextrin [23], phosphatidyl choline [20], and liposomes [25,39], but very little information is available about its biological activities.”
Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment (2011, background): “Moreover, the complex maintained the effective concentrations of curcumin over longer period of time [147].”
Microencapsulation of curcumin in cells of Saccharomyces cerevisiae (2011, background): “3a,i), attributed to the phase transition temperature (Tm) of yeasts‟ phospholipid bilayer from gel to liquid-crystalline state [6, 7].”
Targets of curcumin (2011, background): “These approaches include: the use of adjuvants such as piperine to suppress glucuronidation in the liver [253], the use of liposomal curcumin [259], curcumin nanoparticles [260], the use of curcumin phospholipid complex [261], and the use of structural analogs of curcumin [262].”
Toxicity of lead: A review with recent updates (2012, background): “This is due to its poor aqueous dispersion and poor absorption from the intestine coupled with a high degree of metabolism of curcumin in the liver and rapid elimination in bile (Maiti et al., 2007).”