Biology of interleukin-10.

By R. Sabat, G. Grütz, Katarzyna Warszawska, Stefan Kirsch, Ellen Witte, K. Wolk, J. Geginat. Cytokine & growth factor reviews, 2010

1,037 citations recorded by the source corpus.

Subfields: Immunology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions (2022, background): “Contrary to the aforementioned pro-inflammatory cytokines, IL-10 is released primarily by type-2 helper T cells and serves as an anti-inflammatory cytokine, reducing inflammation and limiting cellular apoptosis.(255) IL-10 gene polymorphism is associated with the risk of stroke subtypes.”
Th2 Cytokines and Atopic Dermatitis (2011, background): “IL-10 is produced by numerous cell types including Th2 cells [141].”
Chronic Inflammation and Cytokines in the Tumor Microenvironment (2014, background): “Almost all immune cells, including T cells, B cells, monocytes, macrophages, mast cells, granulocytes, dendritic cells, and keratinocytes, produce IL-10 [90].”
Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation (2011, neutral): “Unlike several other cell types where IL-10 plays an immunosuppressive function, IL-10 on B cells acts to prevent apoptosis and enhances proliferation, differentiation, and MHC II expression in addition to playing a role in regulation of Ig class switching (Sabat et al., 2010).”