Microbiota regulates immune defense against respiratory tract influenza A virus infection

By T. Ichinohe, I. K. Pang, Yosuke Kumamoto, D. Peaper, J. Ho, T. Murray, A. Iwasaki. Proceedings of the National Academy of Sciences of the United States of America, 2011

1,436 citations recorded by the source corpus.

Subfields: Emergency Medical Services, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/e8e2db27bb973e9b12a2ce3b22a3e0aa221f86a9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Emergency Medical Services

1. Y. Belkaid

In Immunology

1. Y. Belkaid
2. D. Artis
3. Eric G. Pamer
4. E. Wherry
5. Yan Wang
6. L. Kasper
7. B. Rehermann
8. L. Monticelli

In Molecular Biology

1. Y. Belkaid
2. Y. Taur
3. D. Artis
4. Yan Wang
5. Jonathan H. Badger
6. Eric G. Pamer
7. L. Kasper
8. B. Rehermann

Citations in the corpus

• Role of the Microbiota in Immunity and inflammation (2014, background): “This effect of the microbiota can be linked to its capacity to promote the inflammasome-mediated induction of IL-1b and IL-18 secretion (Ichinohe et al., 2011).”
• Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity (2012, background): “Conversely, commensal bacteria can also boost immune responses against mucosal infections (Benson et al., 2009; Hall et al., 2008; Ichinohe et al., 2011; Ivanov et al., 2009).”
• The role of microbiome in central nervous system disorders (2013, positive): “infection with lymphocytic choriomeningitis virus (LCMV) (Abt et al., 2012; Ichinohe et al., 2011).”
• The microbiota of the respiratory tract: gatekeeper to respiratory health (2017, background): “For example, infection by influenza virus was shown to be less efficient following immune priming by lipopoly saccharide (LPS)mediated TLR4 activation of innate immune cells 120, 121 .”
• Wild Mouse Gut Microbiota Promotes Host Fitness and Improves Disease Resistance (2017, positive): “It is well known that the bacterial gut microbiome affects disease outcomes in influenza virus infection (Abt et al., 2012; Ichinohe et al., 2011; Oh et al., 2014) and colorectal tumorigenesis models (Zackular et al., 2013, 2016).”
• Antibiotic-Induced Changes in the Intestinal Microbiota and Disease. (2016, background): “In fact, immunoglobulin titers are decreased in mice treated with antibiotics before viral infection [25,26].”
• The Impact of the Gut Microbiota on Human Health: An Integrative View (2012, neutral): “…disorders are being found to correlate with the host microbiota (recently reviewed in Virgin and Todd, 2011), including susceptibility to influenza (Ichinohe et al., 2011), retrovirus transmission (Kane et al., 2011), colon cancer (Kostic et al., 2011), autoimmune demyelination (Kostic et al.,…”