Role of target geometry in phagocytosis.

By J. Champion, S. Mitragotri. Proceedings of the National Academy of Sciences of the United States of America, 2006

2,001 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy, Physiology

View Paper: https://www.semanticscholar.org/paper/e8bf58cc90539a15bf4e5a4d399c026337c7f3a1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. K. Young
2. S. Mitragotri
3. O. Farokhzad
4. A. Anselmo
5. N. Bertrand
6. P. Couvreur
7. J. Hanes
8. Namho Kim

In Immunology and Allergy

1. K. Young
2. S. Mitragotri
3. O. Farokhzad
4. A. Anselmo
5. N. Bertrand

In Physiology

1. K. Young
2. S. Mitragotri
3. O. Farokhzad
4. A. Anselmo
5. N. Bertrand
6. W. Choi
7. Basit Yameen
8. C. Vilos

Citations in the corpus

• Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. (2014, background): “Nevertheless, this Phase 1 clinical trial did not focus on how the different MPS functions in the tumor correlate with the efficacy of the NPs.”
• Continuous Inertial Focusing and Separation of Particles by Shape (2012, neutral): “[60].”
• Nanoparticles as Drug Delivery Systems: A Review of the Implication of Nanoparticles’ Physicochemical Properties on Responses in Biological Systems (2023, background): “Generally, nanoparticles that are round or spherical in shape are easily endocytosed in comparison to rod or tube-shaped nanoparticles [97].”
• The Selective Value of Bacterial Shape (2006, background): “various sizes, fed them to alveolar macrophages, and found that shape, not size, was the dominant factor in determining whether particles were phagocytized (39).”
• Nanocarriers’ entry into the cell: relevance to drug delivery (2009, background): “This effect, originating in the complexity of actin structure required to initiate uptake, even prevailed on particle size [56].”
• Particle shape: a new design parameter for micro- and nanoscale drug delivery carriers. (2007, background): “We have shown that simple, yet significant, modifications of the stretching protocol can produce over twenty different three dimensional shapes using spheres as small as 200 nm, four of which are shown in Figure 3 [35].”
• Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium (2013, methodology): “Nanorods were fabricated by the film-stretching method described previously (27).”