Biomarkers for epithelial-mesenchymal transitions.

By M. Zeisberg, Eric G. Neilson. Journal of Clinical Investigation, 2009

2,196 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e83129d9722eae6092ff078fd71142cc59343fa6

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Citations in the corpus

Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis (2020, background): “Anatomically, these cells localize to a highly enigmatic region in the IPF lung at the active edge of the myofibroblast foci as we have demonstrated using a combination of markers including p16 (CDKN2A), p21 (CDKN1A), HMGA2, COX2 (PTGS2), p63(TP63), and KRT17.”
The basics of epithelial–mesenchymal transition (EMT): A study from a structure, dynamics, and functional perspective (2019, background): “…increased motility and has the potential to cross through the basal membrane by loosing the adherent and tight junction that helps them to communicate with the neighboring cells (Figure 2; Heerboth et al., 2015; Kalluri & Neilson, 2003; Kim et al., 2017; Son & Moon, 2010; Zeisberg & Neilson, 2009).”
Epithelial-Mesenchymal Transition in Cancer: A Historical Overview (2020, background): “Epithelial-mesenchymal transitions (EMTs), the acquisition of mesenchymal features from epithelial cells, occur during some biological processes and are classified into three types [3,4]: the first type occurs during”
Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression (2010, background): “In addition, biomarkers specific to each subtype of EMT and also common to all subtypes have been defined [22].”
The Molecular Signatures Database (MSigDB) hallmark gene set collection (2015, unknown): “422 Cell Systems 1, 417–425, December 23, 2015 a2015 Elsevier Inc N-cadherin and the Epithelial-Mesenchymal Transition N-cadherin is a marker of mesenchymal cells (Figure 3E) (Zeisberg and Neilson, 2009) and the epithelial-mesenchymal transition (EMT) (Kalluri and Weinberg, 2009).”
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer (2010, background): “For instance, epithelial markers include adherens and tight junction proteins such as E-cadherin and ZO-1, whereas mesenchymal markers include the extracellular matrix component fibronectin and the intermediate filament protein vimentin (Zeisberg and Neilson, 2009).”
Mathematical Modelling of Molecular Pathways Enabling Tumour Cell Invasion and Migration (2015, background): “Gene expression of E-cadherin is inhibited by the transcription factors Snai1/2, Zeb1/2 and Twist1, while gene expression of Ncadherin (cdh2) is induced by the same transcription factors [8,10,11].”
The many faces and functions of β‐catenin (2012, unknown): “In vertebrates, it is active during cell speciﬁcation and lineage determination and is often upregulated during metastasis formation in cancer (Zeisberg and Neilson, 2009; Ansieau et al , 2010).”