Abnormal lymphatic vessel development in neuropilin 2 mutant mice.

By Li Yuan, D. Moyon, L. Pardanaud, C. Bréant, M. Karkkainen, K. Alitalo, A. Eichmann. Development, 2002

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Lymphangiogenesis: Molecular mechanisms and future promise. (2010, background): “The axon guidance receptor neuropilin-2 (NP-2) is expressed in veins and lymphatic vessels, and Np2 mutant mice have lymphatic capillary hypoplasia (Yuan et al., 2002) (Figure 3D).”
Signal transduction by vascular endothelial growth factor receptors. (2012, background): “During development, NRP1 is preferentially expressed in arteries, and NRP2 in veins and lymphatics (Herzog et al. 2001; Yuan et al. 2002; Eichmann et al. 2005; Yaniv et al. 2006).”
Vascular endothelial growth factor (VEGF) signaling in tumor progression. (2007, background): “reported that europilin-2 expression is restricted to veins and lymphatic essels and Np2 null mice exhibit an absence or severe reducion of small lymphatic vessels during development [193].”