Signal transduction by vascular endothelial growth factor receptors.

By S. Koch, L. Claesson‐Welsh. Cold Spring Harbor Perspectives in Medicine, 2012

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The delivery of therapeutic oligonucleotides (2016, background): “Differential expression of certain RTKs is observed in various tissues or disease states including over-expression of HER2 in some forms of breast cancer (102), overexpression of Trk family members in neuronal tissues (103), and enhanced expression of VEGFR2 in vascular endothelial cells (104).”
The roles of vascular endothelial growth factor in bone repair and regeneration (2016, background): “This results in phosphorylation of certain receptor tyrosine residues, and this mediates downstream mitogenic, chemotactic and pro-survival signals [15, 32].”
Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directions (2014, background): “The biology of these interactions has been extensively reviewed [231, 233].”
Vascular endothelial growth factor (VEGF) - key factor in normal and pathological angiogenesis. (2018, background): “Raf/ERK/MAPK pathways [4, 12, 29], these signaling pathways being involved in proliferation of endothelial”