Copper oxide nanoparticles are highly toxic: a comparison between metal oxide nanoparticles and carbon nanotubes.

By H. Karlsson, Pontus Cronholm, J. Gustafsson, L. Möller. Chemical Research in Toxicology, 2008

1,407 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Health, Toxicology and Mutagenesis, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/e6299109adf57b5f42cd48705927f97f45523a91

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. Thomas J. Webster
2. J. Seil
3. Shaily Mahendra
4. P. Alvarez
5. S. Sant
6. Jaesang Lee
7. Rattan Lal
8. P. Ray

In Health, Toxicology and Mutagenesis

1. J. Seil
2. Thomas J. Webster
3. Vyom Sharma
4. A. Dhawan
5. Rattan Lal

In Materials Chemistry

1. Vyom Sharma
2. A. Dhawan
3. Thomas J. Webster
4. J. Seil
5. Diana Anderson
6. Rattan Lal
7. Ruiqiang Liu
8. Huiying Zhang

Citations in the corpus

• Size-dependent toxicity of metal oxide particles--a comparison between nano- and micrometer size. (2009, methodology): “…potential has been demonstrated in lung epithelial cells (A549) following exposure to ambient urban particles (Upadhyay et al., 2003) and asbestos (Kamp et al., 2002) and was recently shown by us after exposure to several particle types including metallic subway particles (Karlsson et al., 2008b).”
• Nanomaterial cytotoxicity is composition, size, and cell type dependent (2010, background): “ROS generation in 3T3 cells exposed to nanoparticles has also been reported by many other groups [14,74].”
• NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials. (2009, background): “[26], who both observed increased strand breakages by the comet assay following the exposure of TiO2 NPs to lung epithelial cells.”
• Toxicity assessment of nanomaterials: methods and challenges (2010, neutral): “Metal oxide NPs Cytotoxicity, membrane damage, inflammatory response, oxidative stress, apoptosis, lysosomal [157–170] Toxicity assessment of nanomaterials: methods and challenges 591”
• Occupational exposure limits for nanomaterials: state of the art (2010, background): “In vitro studies have also shown genotoxic effects for some CNTs (Kisin et al. 2007; Zhu et al. 2007; Karlsson et al. 2008; Muller et al. 2008b; Sargent et al. 2009).”
• Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION) (2010, background): “In fact, magnetite has been shown to cause higher levels of oxidative DNA lesions (using comet assay) in A549 human lung epithelial cell line in the absence of decreased cell viability as compared to maghemite owing to its potential to undergo oxidation (40, 41).”
• Toxicity and Environmental Risks of Nanomaterials: Challenges and Future Needs (2009, neutral): “( 166 ) investigated different nanoparticles and nanotubes regarding cytotoxicity and ability to cause DNA damage and oxidative stress.”
• Nanoparticles as drug delivery systems (2012, background): “Magnetite nanoparticles have the potency of causing oxidative DNA lesions in cultured A549 cells (the human lung epithelial cell line) [70].”
• Antimicrobial applications of nanotechnology: methods and literature (2012, methodology): “9 mV).(32) After 18 hours, cells were rinsed, trypsinated, stained with trypan blue, and counted using a hemocytometer.”
• Nanomaterials in the construction industry: a review of their applications and environmental health and safety considerations. (2010, background): “and DNA damage in bacteria, algae, yeasts, mice, and human cells.(66,96) 98 Mitigation of Public and Environmental Health Impacts.”
• The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles (2012, background): “Karlsson [41] reported that CuO NPs could cause cytotoxicity and DNA damage in the human lung epithelial cell line A549.”