NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials.

By Neenu Singh, B. Manshian, G. Jenkins, S. M. Griffiths, P. Williams, T. Maffeis, C. Wright, S. Doak. Biomaterials, 2009

1,143 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/412e7ccd0bb7bb86c9a2449e38f434f3296405d2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. N. Bertrand
2. Xiaoyang Xu
3. Paul Rees
4. O. Farokhzad
5. M. Brown
6. Sumit Arora
7. Mark D. Holton
8. Huw D. Summers

In Materials Chemistry

1. F. Pacheco-Torgal
2. Paul Rees
3. O. Farokhzad
4. M. Brown
5. Sumit Arora
6. Mark D. Holton
7. Huw D. Summers
8. G. Xing

In Molecular Biology

1. N. Bertrand
2. Xiaoyang Xu
3. O. Farokhzad
4. Sumit Arora
5. Eric M. Pridgen
6. Xue-Qing Zhang
7. A. Swami
8. K. Paknikar

Citations in the corpus

• Genotoxic effects of zinc oxide and titanium dioxide nanoparticles on root meristem cells of Allium cepa by comet assay (2014, background): “For these reasons nanotoxicology and nanogenotoxicology are expanding as novel fields that are looking for the potential risk of nanomaterials as well as their possible mechanisms of action (Landsiedel et al., 2009; Singh et al., 2009; Ai et al., 2011).”
• Nanotechnology: Advantages and drawbacks in the field of construction and building materials (2011, background): “[84] mentioned the possibility of DNA damage resulting in later cancer development.”
• Nanotoxicology and in vitro studies: the need of the hour. (2012, background): “Singh et al. (2009) have reviewed the abilities of metal nanoparticles, metal-oxide nanoparticles, quantum dots, fullerenes, and fibrous nanomaterials, with reference to their potential to damage or interact with DNA.”
• Quantitative characterization of nanoparticle agglomeration within biological media (2012, positive): “) (Hardman 2006; Singh et al. 2009; Yang et al. 2008).”
• Toxicity assessment on haemotology, biochemical and histopathological alterations of silver nanoparticles-exposed freshwater fish Labeo rohita (2015, background): “Furthermore, nanoparticles are also shown to cause toxicity by increasing concentration of intracellular ROS and decrease in antioxidant level (Singh et al. 2009; Hussain et al. 2009).”
• The current application of nanotechnology in food and agriculture (2018, neutral): “Overproduction of ROS can lead to autophagy [89], neuron damage [90], and severe damage to DNA [78,91], and potentially mutagenesis, carcinogenesis, and aging-related diseases in humans.”
• The Toxic Effects and Mechanisms of CuO and ZnO Nanoparticles (2012, background): “In addition, increased ROS induced by NPs in lysosomes can cause DNA point mutations or induce single- or double-strand breaks [111].”
• Interactions of nanomaterials and biological systems: implications to personalized nanomedicine (2012, background): “Some nanomaterials such as metal nanoparticles, metal oxide nanoparticles, QDs, fullerenes and fibrous nanomaterials were found to induce chromosomal fragmentation, DNA strand breakages, point mutations, oxidative DNA adducts and alterations in gene expression [198], sometimes even through cellular ”