A meta-analysis of structural brain abnormalities in PTSD.

By A. Karl, Michael Schaefer, Loretta S. Malta, Denise Dörfel, Nicolas Rohleder, Annett Werner. Neuroscience and Biobehavioral Reviews, 2006

866 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Clinical Psychology, Developmental Neuroscience

View Paper: https://www.semanticscholar.org/paper/e4eac820b7d25f2d7065ba88057e7c2427d626a9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Diego A. Pizzagalli
2. Thomas Elbert
3. Richard J. Davidson
4. Morten L. Kringelbach
5. Israel Liberzon
6. Iris-Tatjana Kolassa
7. Pia Pechtel
8. Elizabeth A. Shirtcliff

In Clinical Psychology

1. Diego A. Pizzagalli
2. Iris-Tatjana Kolassa
3. Richard J. Davidson
4. C. Kwon
5. Thomas Elbert
6. Israel Liberzon
7. L. Parada
8. Pia Pechtel

In Developmental Neuroscience

1. Thomas Elbert
2. Israel Liberzon
3. Lisa M. Shin

Citations in the corpus

• Structural and Functional Neuroplasticity in Relation to Traumatic Stress (2007, methodology): “Abnormalities in the size of various brain structures in PTSD are not restricted to the hippocampus, although the effect sizes in other brain structures are smaller than in the hippocampus (Karl et al., 2006).”
• Annual Research Review: Enduring neurobiological effects of childhood abuse and neglect (2016, neutral): “Further, a meta-analysis of PTSD studies revealed greater effects of trauma exposure on hippocampal volume in males than females (Karl et al., 2006).”
• Great Expectations: Using Whole-Brain Computational Connectomics for Understanding Neuropsychiatric Disorders (2014, background): “Damage to the structural connectome can therefore have potentially very severe impact on the resulting functional connectivity.”
• TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment (2008, background): “Similarly, reduction of hippocampal volume has been reported in some studies of human patients with major depression (Bremner et al., 2000; MacQueen et al., 2003) and posttraumatic stress disorder (Gilbertson et al., 2002; Karl et al., 2006; Smith, 2005).”
• Effects of Early Life Stress on Cognitive and Affective Function: An Integrated Review of Human Literature (2010, background): “Numerous studies have failed to demonstrate volumetric reductions in younger individuals with ELS (Carrion et al. 2001; De Bellis et al. 2002b; De Bellis et al. 2010; Teicher et al. 2003; see meta-analyses by Karl et al. 2006; Woon and Hedges 2008; Woon et al. 2010 ).”
• Behavior Problems After Early Life Stress: Contributions of the Hippocampus and Amygdala (2014, result): “However, similar agreement does not exist for the hippocampus and amygdala, with inconsistent results being reported even in meta-analyses on the neurobiological effects of trauma (29,30).”
• The Neurocircuitry of Fear, Stress, and Anxiety Disorders (2011, background): “…volumes appear to be diminished in PTSD in some (Bossini et al, 2008; Bremner et al, 1995, 1997, 2003a; Gilbertson et al, 2002; Gurvits et al, 1996; Karl et al, 2006; Kitayama et al, 2005; Smith, 2005; Stein et al, 1997; Villarreal et al, 2002a; Wignall et al, 2004; Winter and Irle, 2004; Woon and…”