Commercial-scale Preparation of Biofunctional Fucoxanthin from Waste Parts of Brown Sea Algae Laminalia japonica

By K. Kanazawa, Y. Ozaki, T. Hashimoto, Swadesh K. Das, Saori Matsushita, M. Hirano, T. Okada, Akitoshi Komoto, Nobuki Mori, Masahiro Nakatsuka. 2008

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Bioactive compounds in seaweed: functional food applications and legislation (2011, background): “The fucoxanthin obtained was stable and reduced by only 2% at 4°C in 6 months of storage (Kanazawa et al. 2008).”
Red and green macroalgae for fish and animal feed and human functional food development (2016, background): “of fucoxanthin (178–196 mg/kg fresh weight) to the harvested macroalgae, with a recovery ratio of 82%.((50)) Oxidative stress was reported previously as an important process in the development of the pathogenesis of several diseases, and natural antioxidants have received attention for their possibl”
Fucoxanthin as a major carotenoid in Isochrysis aff. galbana: Characterization of extraction for commercial application (2012, background): “However, although fucoxanthin is clearly a valuable pigment with various biological activities, its use has been limited due to the low extraction efficiency from marine materials and the difficulty of chemical synthesis (Yamano et al., 1995; Kanazawa et al., 2008; Kajikawa et al., 2012).”