Transmembrane crosstalk between the extracellular matrix and the cytoskeleton

By Benjamin Geiger, A. Bershadsky, R. Pankov, Kenneth M. Yamada. Nature reviews. Molecular cell biology, 2001

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Get a ligand, get a life: integrins, signaling and cell survival (2002, background): “Thus, different ligands, or different forms of a particular ligand, can transmit distinct signals to a cell through the same integrin (Geiger et al., 2001; Koo et al., 2002; Stupack et al., 1999).”
Revealing Early Steps of α2β1 Integrin-mediated Adhesion to Collagen Type I by Using Single-Cell Force Spectroscopy (2007, background): “In adherent cells, integrins are often arranged into highly organized structures, such as focal complexes, focal adhesions, and fibrillar adhesions (Geiger et al., 2001).”
Adhesion-dependent cell mechanosensitivity. (2003, background): “…events are executed in the adhesion plaques by several types of enzymes, including protein tyrosine kinases [e.g., focal adhesion kinase (FAK), Src, Fyn, etc.] (Geiger et al. 2001, Zamir & Geiger 2001); protein tyrosine phosphatases [e.g., receptor-like tyrosine phosphataseα (RPTP-α)] (Von A nn u.”
Fibronectin at a glance (2002, background): “The creation and deposition of insoluble FN fibrils into the ECM is a tightly regulated, cellmediated process termed FN fibrillogenesis or FN matrix assembly (for a review, see Geiger et al., 2001).”