Drosophila immunity: two paths to NF-κB

By R. Khush, F. Leulier, B. Lemaître. 2001

162 citations recorded by the source corpus.

Subfields: Ecology, Evolution, Behavior and Systematics, Immunology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/e3a29891a5f2be76788854b5dc35577c366e0534

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Shizuo Akira
2. K. Takeda
3. R. Medzhitov
4. J. Hoffmann
5. T. Kaisho
6. Taro Kawai
7. O. Takeuchi
8. J. Reichhart

In Infectious Diseases

1. R. Medzhitov
2. Shizuo Akira

Citations in the corpus

• Toll-like receptors. (2003, background): “Mutant flies lacking 18-wheeler, a member of the Toll family, are susceptible to Gram-negative bacterial infection, but expression of Diptericin is normal in these mutants (23, 24).”
• Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein (2001, background): “jpg" NDATA ITEM> ]> Microbial infection activates two distinct intracellular signalling cascades in the immune-responsive fat body of Drosophila”
• Toll-like receptors and innate immunity (2001, background): “Interestingly, the Toll pathway can also be activated in response to Gram-positive infection, indicating that several pattern-recognition molecules might function upstream of the protease cascade that controls cleavage of Spatzl”