Hedgehog signals regulate multiple aspects of gastrointestinal development.

By M. Ramalho-Santos, D. Melton, Andrew P. McMahon. Development, 2000

867 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/e313c95b26209908b181d4cb15aabf89d37c82a8

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Citations in the corpus

Feeding behaviour and digestive physiology in larval fish: current knowledge, and gaps and bottlenecks in research (2013, background): “…that are associated with a drastic change in diet from suckling to solid food in mammals, or from herbivorous to carnivorous in amphibian (Henning 1979; Buddington 1994; Ramalho-Santos et al. 2000; Shi & Ishizuya-Oka 2001; Zabielski et al. 2008; Schreiber et al. 2009; Heimeier et al. 2010).”
Depletion of definitive gut endoderm in Sox17-null mutant mice. (2002, background): “During gut development, Sonic hedgehog (Shh) and Indian hedgehog (Ihh) are expressed in the endoderm and play crucial roles in the regionalisation of the primitive gut tube (Apelqvist et al., 1997; Hebrok et al., 1998; Ramalho-Santos et al., 2000; Sukegawa et al., 2000).”
Hedgehog signaling in animal development: paradigms and principles. (2001, background): “Although Ptc is clearly a Hh receptor, recent evidence inDrosophila has indicated that Hh can in some circumstances signal to cells by a Ptc-independent mechanism (Ramirez-Weber et al. 2000).”
Wnt signaling in the intestinal epithelium: from endoderm to cancer. (2005, background): “During chick and mouse development Sonic hedgehog (Shh) and Indian hedgehog (Ihh) play multiple roles in patterning of the gastrointestinal tract (Apelqvist et al. 1997; Litingtung et al. 1998; Ramalho-Santos et al. 2000; Sukegawa et al. 2000; Fukuda et al. 2003).”
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. (2001, background): “…signaling has been implicated in regulating cell proliferation in a variety of vertebrate tissues, studies so far have been based largely on manipulating Hh expression (Dahmane and Ruiz-i-Altaba, 1999; Marcelle et al., 1999; Ramalho-Santos et al., 2000; Rowitch et al., 1999; Treier et al., 2001).”