Chitosan: some pharmaceutical and biological aspects ‐ an update

By A. K. Singla, Manisha Chawla. The Journal of pharmacy and pharmacology, 2001

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Chitosan and its antimicrobial potential – a critical literature survey (2009, background): “…chitosan solutions show pseudoplastic and viscoelastic properties; their viscosity is affected by chitosan’s DD, MW and concentration, concentration and types of solvents, the prevailing solution pH and ionic strength, as well as temperature (Chen and Tsaih, 1998; Singla and Chawla, 2001).”
Chitosan microspheres as a potential carrier for drugs. (2004, background): “Chitin is a straight homopolymer composed of -(1,4)-linked N-acetyl-glucosamine units while chitosan comprises of copolymers of glucosamine and N-acetyl-glucosamine (Kas, 1997; Singla and Chawla, 2001; Kato et al., 2003).”
Insights into the Mode of Action of Chitosan as an Antibacterial Compound (2008, background): “Its oral mean lethal dose in mice was found to be in excess of 16 g/day/kg of body weight, which is higher than that of sucrose (13, 41).”
The magic glue hyaluronan and its eraser hyaluronidase: a biological overview. (2007, background): “, 2003), and immune enhancing activities (Singla and Chawla, 2001; Senel and McClure, 2004).”
Chitosan: A Natural Biopolymer with a Wide and Varied Range of Applications (2020, background): “On the other hand, chitosan has been also used in tissue regeneration and restoration due to its biodegradability and cell affinity [67].”