Insights into the Mode of Action of Chitosan as an Antibacterial Compound

By Dina Raafat, Kristine von Bargen, A. Haas, H. Sahl. Applied and Environmental Microbiology, 2008

779 citations recorded by the source corpus.

Subfields: Biomaterials, Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4d9e80ec3093b3dd299158e28cb338c949756529

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. Peter A. Williams
2. M. Kaya
3. Kabil Özcan Tozak
4. A. Menteş
5. T. Baran
6. O. Tverezovskaya
7. M. H. Mohammed

In Molecular Biology

1. M. Kaya
2. T. Baran

Citations in the corpus

• Extraction and characterization of chitin and chitosan with antimicrobial and antioxidant activities from cosmopolitan Orthoptera species (Insecta) (2015, background): “[56] determined the effectiveness of chitosan (purchased from Sigma-Aldrich) against Staphylococcus aureus SG511 and found that the MBC value was 31.”
• Occurrence of Escherichia coli O157 in a river used for fresh produce irrigation in Nigeria. (2010, background): “Raafat reported that molecules of chitosan larger than 10 kDa were responsible for its antimicrobial activity (Raafat et al., 2008).”
• Modification of Chitosan for the Generation of Functional Derivatives (2019, background): “The activity is also modulated by the culture medium composition and it is different in laboratory media and in foods [95,98,134]: lipids, proteins, and divalent metal cations can bind to CS and prevent its interaction with target microbes [103].”
• Chitosan-Based Coating with Antimicrobial Agents: Preparation, Property, Mechanism, and Application Effectiveness on Fruits and Vegetables (2016, background): “[105] also demonstrated that the binding of chitosan to teichoic acids accompanied by the extraction of membrane lipids could induce the death of bacteria.”
• Antimicrobial properties of chitosan and mode of action: a state of the art review. (2010, background): “In one such recent study (Raafat et al., 2008), the transcriptional response pattern to chitosan revealed 166 open reading frames that showed a statistically significant (at 0.”