Regulation of firing of dopaminergic neurons and control of goal-directed behaviors.

By Anthony A. Grace, S. Floresco, Yukiori Goto, D. Lodge. Trends in Neurosciences, 2007

1,049 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/e2e42f379da485a36d3a1788ab5af27170b6ab74

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Citations in the corpus

Cortico-Basal Ganglia Reward Network: Microcircuitry (2009, neutral): “Thus, the vSub provides a contextdependent modulation of the amplitude of the DA response to stimuli (Grace et al, 2007).”
Dopamine System Dysregulation in Major Depressive Disorders (2017, background): “As previously described in numerous reviews (Grace, 1991, 2016; Grace et al., 2007; Belujon and Grace, 2015), the mesolimbic DA neurons can display multiple activity states.”
The Adolescent Brain (2008, background): “…have shown that dopamine is crucial for communication between the accumbens, amygdala, and prefrontal cortex and that signaling between these regions relies upon the fine balance between excitatory and inhibitory dopamine transmission (Floresco & Tse 2007; Grace et al. 2007; Jackson et al. 2001).”
Phasic excitation of dopamine neurons in ventral VTA by noxious stimuli (2009, neutral): “It has been suggested that using a high-pass filter setting of 50 Hz is important for distinguishing between dopaminergic and nondopaminergic VTA neurons on the basis of their AP waveform (17).”
Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. (2008, neutral): “Even at the level of the well-studied basic electrophysiological properties of DA midbrain neurons (Grace et al., 2007; Schultz, 2007), the degree of functional diversity associated with distinct axonal targets remains unresolved.”
Burst timing-dependent plasticity of NMDA receptor-mediated transmission in midbrain dopamine neurons: A putative cellular substrate for reward learning (2009, neutral): “content of the downstream DA signal are changes in firing pattern (from tonic firing to bursting or from tonic firing to pausing) (Niv, 2007; Schultz, 2007) and recruitment of larger or smaller assemblies of DA neurons to these firing pattern transitions (Floresco et al., 2003; Grace et al., 2007; N”
Beyond classical benzodiazepines: Novel therapeutic potential of GABAA receptor subtypes (2011, background): “, activates tonic firing of dopaminergic neurons in the midbrain; this circuit involves glutamatergic neurons in the hippocampus, GABAergic neurons in the nucleus accumbens and GABAergic neurons in the ventral pallidu”
Dopamine in motivational control: rewarding, aversive, and alerting (2010, background): “The PPTg is important for enabling VTA DA neuron bursts (Grace et al., 2007) including burst responses to reward cues (Pan and Hyland, 2005).”
Cognitive Control of Drug Craving Inhibits Brain Reward Regions in Cocaine Abusers (2009, background): “…by glutamatergic projections from the frontal cortex (You et al., 2007; Yun et al., 2004; Taber et al., 1995), including the orbitofrontal cortex (OFC), which signals the motivational value of the conditioned stimuli (Rolls, 1996) and from amygdala and ventral hippocampus (Grace et al., 2007).”