Ectosomes and exosomes: shedding the confusion between extracellular vesicles.

By Emanuele Cocucci, J. Meldolesi. Trends in Cell Biology, 2015

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Inflammaging and 'Garb-aging'. (2017, background): “These molecules can trigger a feed-forward propagation/amplification cycle of inflammation/inflammaging, where different shuttles actively secreted by cells such as exosomes and ectosomes - generally defined as extracellular vesicles (EVs) [70] - are involved.”
Extracellular miRNAs: From Biomarkers to Mediators of Physiology and Disease (2019, background): “Direct budding can also produce small vesicles similar to exosomes which have been termed shed vesicles or ectosomes (Booth et al., 2006; Cocucci and Meldolesi, 2015).”
Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes (2019, background): “It begins with the in-budding of endosomes, which in turn forms MVBs that contain intra-luminal vesicles (ILVs) [42,43].”
Tumor-derived exosomes and their role in cancer progression (2016, background): “Skog detected mRNA coding the mutant epidermal growth factor receptor (EGFRvIII) in EVs derived from plasma of patients with glioblastoma [80].”
The biology, function, and biomedical applications of exosomes (2020, neutral): “Although the classification of EVs is continuously evolving (1), they generally fall into twomajor categories, ectosomes and exosomes (10) (Fig.”