Vascular endothelial growth factor‐C‐mediated lymphangiogenesis promotes tumour metastasis

By S. J. Mandriota, L. Jussila, M. Jeltsch, A. Compagni, D. Baetens, R. Prevo, Suneale Banerji, J. Huarte, R. Montesano, D. Jackson and 4 more. EMBO Journal, 2001

987 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/aa8006deec010911bb90ecf9c0a11fc5452c5c95

How researchers see this paper

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In Molecular Biology

1. K. Alitalo
2. Peter Carmeliet
3. T. Tammela
4. H. Wildiers
5. A. V. van Oosterom
6. A. Hoeben
7. E. D. de Bruijn
8. M. Highley

In Oncology

1. K. Alitalo
2. T. Tammela
3. Peter Carmeliet
4. M. Shibuya
5. Rakesh K. Jain
6. N. Ferrara
7. M. Swartz
8. H. Wiig

In Surgery

1. K. Alitalo

Citations in the corpus

• Lymphangiogenesis in development and human disease (2005, background): “High levels of VEGF-C or VEGF-D also enhance lymphatic metastasis in various experimental model”
• Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3 (2001, background): “Many tumors metastasize through the lymphatic vessels and VEGF-C and/or VEGF-D expression in tumor cells has been linked to lymphangiogenesis associated with tumors, invasion of cancer cells into the lymphatic vessels and lymph node metastasi”
• Molecular mechanisms of lymphangiogenesis in health and disease. (2002, background): “Transgenic mice overexpressing VEGF-C in β cells of the endocrine pancreas developed extensive lymphangiogenesis around the endocrine islets of Langerhans (Mandriota et al., 2001).”
• Current Challenges and Opportunities in Treating Glioblastoma (2018, background): “…amino acid transporter (Gomes and Soares-da-Silva, 1999), glucose transporter (Fernández et al., 2003), sodium-dependent vitamin C transporter 2 (Manfredini et al., 2002), peptide transporters, monocarboxylic acid transporters, organic cation transporters, organic anion transporters, and…”
• Vascular Endothelial Growth Factor and Angiogenesis (2004, background): “Since experiments with lymph vessels are difficult to conduct, a direct causal role for VEGF-C-mediated lymphangiogenesis in the dissemination of tumor cells was demonstrated only in 2001 using a transgenic mouse model of nonmetastatic -cell carcinogenesis (Mandriota et al., 2001).”