Glutathione peroxidase 1 activity and cardiovascular events in patients with coronary artery disease.

By Stefan Blankenberg, H. Rupprecht, C. Bickel, M. Torzewski, G. Hafner, L. Tiret, M. Smieja, F. Cambien, Jürgen Meyer, K. Lackner. New England Journal of Medicine, 2003

621 citations recorded by the source corpus.

Subfields: Biochemistry, Immunology, Physiology

View Paper: https://www.semanticscholar.org/paper/e006a31a58c36631ee9f04d9e597a9668c229a7f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. U. Förstermann
2. Huige Li
3. Sven Horke
4. J. Keaney

In Immunology

1. R. Stocker
2. U. Förstermann
3. J. Keaney

In Physiology

1. U. Förstermann
2. Huige Li
3. Sven Horke
4. K. Sugamura
5. J. Keaney

Citations in the corpus

• Reactive Oxygen Species in Cardiovascular Disease (2011, background): “The cellular antioxidant enzyme, glutathione peroxidase-1 (GPX-1) activity was decreased in CAD patients and lower GPX-1 activity predicted the incidence of cardiovascular events at five years [223].”
• Vascular oxidative stress, nitric oxide and atherosclerosis. (2014, background): “In patients with coronary artery diseas , the activity of red blood cell GPx1 is inversely associated with the risk of cardiovascula r events [85].”
• Role of oxidative modifications in atherosclerosis. (2004, background): “Evidence for the contribution of oxidative events in the precipitation of cardiovascular events comes from studies showing that in patients with coronary artery disease low red blood cell peroxidase 1 activity (66) or increased plasma levels of myeloROLE OF OXIDATIVE MODIFICATIONS IN ATHEROSCLEROSIS”
• Vascular Inflammation and Oxidative Stress: Major Triggers for Cardiovascular Disease (2019, background): “A study of 636 individuals showed a positive correlation between levels of glutathione peroxidase-1, an antioxidant enzyme, and cardiovascular event-free survival [113].”
• Biological markers of oxidative stress: Applications to cardiovascular research and practice (2013, background): “In a prospective study of patients with suspected coronary artery disease, erythrocyte GPX-1 and not SOD activity was inversely associated with incidence of cardiovascular events after adjusting for cardiovascular risk factors [90].”
• Glutathione Peroxidase-1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities (2011, neutral): “In the AtheroGene prospective study of 636 patients with coronary heart disease, GPx-1 activity was one of the strongest univariate predictors of future cardiovascular events, and the risk of future cardiovascular events was inversely related to erythrocyte GPx-1 activity levels (40).”