The repair of double-strand breaks in plants: mechanisms and consequences for genome evolution.
By Holger Puchta. Journal of Experimental Botany, 2004
625 citations recorded by the source corpus.
Subfields: Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/dff9385aee4dc133f2769518d156c1b439e59f2f
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Michael J Bozzella
- Vera Gorbunova
- R. Fischer
- Z. Mao
- Daniel F. Voytas
- Virginia Walbot
- Andrei Seluanov
- L. Bortesi
In Plant Science
- Michael J Bozzella
- Vera Gorbunova
- R. Fischer
- Z. Mao
- Daniel F. Voytas
- Virginia Walbot
- Andrei Seluanov
- L. Bortesi
Citations in the corpus
- Genome Editing of Plants (2017, background): “If the break is repaired by homologous recombination (HR), information is copied from a DNA template during the repair process (Puchta, 2005).”
- Comparison of nonhomologous end joining and homologous recombination in human cells (2008, background): “Yeast rely heavily on HR while in mammals and plants NHEJ is the preferred pathway [11,12].”
- Advancing Crop Transformation in the Era of Genome Editing[OPEN] (2016, background): “This pathway often results in small changes at the repaired site and can be used to perform targeted mutagenesis to alter gene expression or function (Puchta, 2005; Wang et al., 2014; Li et al., 2012).”
- The CRISPR/Cas9 system for plant genome editing and beyond. (2015, background): “Even though the generation of breaks in both DNA strands induces recombination at specific genomic loci, NHEJ is by far the most common DSB repair mechanism in most organisms, including higher plants, and the frequency of targeted integration by HR remains much lower than random integration (Puchta,”