Molecular identification of bacteria associated with bacterial vaginosis.

By David N. Fredricks, T. Fiedler, J. Marrazzo. New England Journal of Medicine, 2005

1,235 citations recorded by the source corpus.

Subfields: Clinical Biochemistry, Epidemiology, Microbiology

View Paper: https://www.semanticscholar.org/paper/bcf5c376cc4a81ce4a9305bea2ac18cb87d83967

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In Clinical Biochemistry

1. P. Weimer
2. D. Stevenson
3. A. Wolfe
4. E. Costello

In Epidemiology

1. P. Weimer
2. D. Stevenson
3. Curtis Huttenhower
4. Roberto Romero
5. David A. Relman

In Microbiology

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2. D. Stevenson
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Citations in the corpus

• Bacterial Communities in Women with Bacterial Vaginosis: High Resolution Phylogenetic Analyses Reveal Relationships of Microbiota to Clinical Criteria (2012, methodology): “For example, BVassociated bacterium-1 (BVAB-1), BVAB-2 and BVAB-3 are novel bacteria in the Clostridiales Order that are highly specific for BV [18].”
• The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women (2014, background): “The use of molecular culture-independent techniques has increased the knowledge about the complexity of the microbial ecosystem of multiple body sites, including the human vagina [21,26,40,41,47,76,92-110].”
• Dominance of Prevotella and low abundance of classical ruminal bacterial species in the bovine rumen revealed by relative quantification real-time PCR (2007, positive): “…(FISH) permits both quantitation and direct visualization of specific taxa and was used to quantify Prevotella and other taxa in environmental samples lacking large amounts of particulate matter yielding results similar to parallel measurements using real-time PCR (Fredricks et al. 2005).”
• High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence. (2006, background): “With recurrence 25 (23 [16-321) 36 (33 [25-42]) 49 (43 [34-521) 63 (54 [45-631) 59 (52 [43-611) 74 (64 [55-731) 68 (58 [49-66]) 84 (69 [61-77])”
• Short-chain fatty acids: linking diet, the microbiome and immunity (2024, neutral): “During bacterial vaginosis, several types of anaerobic bacteria including Gardnerella vaginalis dominate the vaginal microbiota 222 , shifting metabolites towards lower lactic acid levels and synthesis of high levels of butyrate, propionate and acetate 223 .”
• Microbiota in health and diseases (2022, background): “, Lactobacillus species).(45) Moreover, the vaginal microbial community is overabundant with anaerobic bacteria including Gardnerella vaginalis, Prevotella spp.”
• Evidence of Uncultivated Bacteria in the Adult Female Bladder (2012, methodology): “Sequence analysis of 16S rRNA, the workhorse of 61 that effort, has been used to determine the microflora composition of healthy skin (12, 13), 62 gastrointestinal tract (7, 9, 36), mouth (24, 25, 28), and vagina (11, 16, 27, 39), and to correlate 63 certain diseases with changes in composition (9, ”
• Mucosal Immunity in the Female Genital Tract, HIV/AIDS (2014, background): “Bacterial vaginosis is a condition caused by an alteration in the genital tract flora in which lactobacilli are predominantly replaced by anaerobic bacteria, including Gardnerella vaginalis, Mycoplasma hominis, and Atopobium vaginae as well as species of Prevotella, Mobiluncus, and Peptostreptococcu”
• Temporal and spatial variation of the human microbiota during pregnancy (2015, background): “Preterm birth also is associated with bacterial vaginosis, a community-wide alteration of the vaginal microbiota (10, 11) that increases the risk of preterm birth approximately twofold (12, 13).”
• The healthy human microbiome (2016, background): “The principle that high diversity is “healthy” does not hold for all body sites, however, as diversity in the vaginal microbiome can be associated with bacterial vaginosis [108], cervical intraepithelial neoplasia [109] (an abnormal growth on the cervix), pre-term birth [36], and inflammation [110].”