Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells

By O. Mandelboim, N. Lieberman, M. Lev, Lada Paul, T. Arnon, Y. Bushkin, D. Davis, J. Strominger, J. Yewdell, A. Porgador. Nature, 2001

1,063 citations recorded by the source corpus.

Subfields: Epidemiology, Genetics, Immunology

View Paper: https://www.semanticscholar.org/paper/de8ae1643c91c72fd5fd68da8bded41250e3d22c

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In Epidemiology

1. O. Levy
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In Immunology

1. Eric O Long
2. H. Ljunggren
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Citations in the corpus

• The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity (2009, background): “The NK cell-mediated killing is extracted by specific receptors, among which are the natural cytotoxicity receptors (NCRs), which include the NKp30 that interacts with pp65 of human cytomegalovirus (CMV), BAT3 and the recently identified B7-family member B7-H6 (9–11), and the NKp46/NKp44 receptors, ”
• Modulation of natural killer cell activity by viruses (2010, neutral): “The number of NK cells expressing the activating receptors NKp30 and NKp46, KIR3DL1 or Curr Opin Microbiol.”
• A novel influenza A virus mitochondrial protein that induces cell death (2001, background): “This indicates that PB1-F2 may function in vivo to disable IAV-infected monocytes or other host innate immune cells (such as the subset of NK cells specific for viruses that express sialic acid glycoprotein”
• Activation, coactivation, and costimulation of resting human natural killer cells (2006, background): “Arnon TI, et al. The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46.”
• Natural killer cells, viruses and cancer (2001, background): “, and NKp44 and NKp46 have been reported to bind the haemagglutinin of influenza virus due to the presence of sialic acid on these receptor”
• Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. (2012, background): “, 1980), which respond to viral infections (Mandelboim et al., 2001).”
• NK cells and cancer immunosurveillance (2008, background): “In contrast, several viral structures binding to NCR were described, including hemagglutinins of influenza and sendai viruses (to NKp46 and NKp44) and pp65 tegument protein of human cytomegalovirus (to NKp30) (Mandelboim et al., 2001; Arnon et al., 2005, 2006).”
• Decidual NK cells regulate key developmental processes at the human fetal-maternal interface (2006, background): “32 ), viral proteins (such as hemagglutinin) or pp65 (ligands for NKp44, NKp46 and NKp30, respectivel”