Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms

By M. Rondon, P. August, A. Bettermann, S. Brady, T. Grossman, M. Liles, K. Loiacono, B. Lynch, I. Macneil, Charles Minor and 6 more. Applied and Environmental Microbiology, 2000

1,271 citations recorded by the source corpus.

Subfields: Ecology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/ddec9744cf9728d0b02d5716999dffb437e13d8e

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Citations in the corpus

Metagenomics: genomic analysis of microbial communities. (2004, methodology): “Significant progress has been made, producing libraries that have substantially advanced understanding the functions in the soil community (96).”
Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae. (2002, neutral): “AarA has homology to Rhomboid (RHO), which has been primarily studied in Drosophila melanogaster ( Rather et al., 1999 ).”
Endophytic fungal diversity: review of traditional and molecular techniques (2012, background): “A metagenomic library has been successfully constructed for natural product screening in soil microbes (Rondon et al. 2000; Clardy et al. 2006).”
Phymm and PhymmBL: Metagenomic Phylogenetic Classification with Interpolated Markov Models (2009, neutral): “By sequencing collections of organisms from environments ranging from the human body to soil to the ocean floor, metagenomics projects are vastly increasing the range of organisms that can be analyzed, allowing for systems-level study of microbial environments and revealing a heretofore hidden world”
Lignocellulose biotechnology: issues of bioconversion and enzyme production (2003, background): “Laccases can degrade a wide variety of synthetic dyes making them suitable for the treatment of wastewater from the textile industry (Rosales et al., 2002).”
Microbial populations responsible for specific soil suppressiveness to plant pathogens. (2002, background): “For dissection of community structure at the species or subspecies level, PCR primers also can be developed from clones of the targeted DNA fragments themselves, as was done to identify phlD+ strains (134), molecular markers derived from related isolates, or sequences linked to the original target s”