IL-6 in autoimmune disease and chronic inflammatory proliferative disease.

By K. Ishihara, T. Hirano. Cytokine & growth factor reviews, 2002

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How researchers see this paper

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IL-6 signaling in autoimmunity, chronic inflammation and inflammation-associated cancer. (2011, neutral): “autoimmune diseases [23].”
IL-6 in inflammation, autoimmunity and cancer (2020, background): “Among them, IL-6 is a major player in chronic inflammatory diseases, autoimmune diseases, cancer and cytokine storm (1, 3, 10–26).”
The role of IL-6 and STAT3 in inflammation and cancer. (2005, background): “In multiple myeloma patients, serum IL-6 levels are elevated and this is correlative with an unfavorable outcome [59,60].”
A cytokine-mediated link between innate immunity, inflammation, and cancer. (2007, positive): “IL-6 IL-6 is a potent pleiotropic inflammatory cytokine that is considered a key growth-promoting and antiapoptotic factor (55).”
IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages (2003, background): “IL-6, which activates STAT3, has been proposed to contribute to the progression of many inflammatory disease such as rheumatoid arthritis and Crohn diseas”