Role of the gut microbiota in nutrition and health

By Ana M. Valdes, J. Walter, E. Segal, Timothy D. Spector. British medical journal, 2018

3,227 citations recorded by the source corpus.

Ana M Valdes and colleagues discuss strategies for modulating the gut microbiota through diet and probiotics

Subfields: Molecular Biology, Physiology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/dd412d1d34d41d8d899d4628270e1fc74959248f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

In Physiology

In Public Health, Environmental and Occupational Health

Citations in the corpus

What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases (2019, background): “The gut microbiome encodes over 3 million genes producing thousands of metabolites, whereas the human genome consists of approximately 23,000 genes [3].”
Gut Microbiota and Short Chain Fatty Acids: Implications in Glucose Homeostasis (2022, background): “In addition, following dietary changes, including habitual fiber intake, can select fiberfermenting microbes, which, in turn, will inhibit other harmful species [94].”
Kynurenine pathway metabolism and the microbiota‐gut‐brain axis (2017, background): “An alternative view is that the gut microbial composition reflects a core set of functional profiles in which some bacterial species are more critically involved in the functional profile and may thus influence, to a greater degree, health and disease (Flint et al., 2012).”
Gut Microbiome: Profound Implications for Diet and Disease (2019, background): “Fruits and vegetables; prebiotic-containing foods [4] Low fiber intake/low FODMAP carbs [244] Beer, bread, sugar/artificially-sweetened beverages [120,122]”
Butyrate: A Double-Edged Sword for Health? (2018, background): “Among the SCFAs, butyrate is the most potent in inhibiting HDAC activities both in vitro and in vivo (53, 54).”
Characterization of the Gut Microbiome Using 16S or Shotgun Metagenomics (2016, methodology): “For instance, it is well known that bacteria aid in many importantmetabolic pathways, including synthesis of essential compounds like secondary bile acids and short-chain fatty acids (Flint et al., 2012; Nicholson et al., 2012).”
Interplay between the human gut microbiome and host metabolism (2019, background): “Although the external environment plays an important role in shaping the gut microbiome community, the host can affect the microbial ecosystem through its immune system, and has also a metabolic impact on the gut lumen [7,8,9].”
Microbiota in health and diseases (2022, background): “Instead, Bacteriodetes such as Bacteroidaceae, Prevotellaceae and Rikenellaceae are often found in the colon.(19) Such variations are majorly due to the different environments.”
The Human Gut Microbiome: From Association to Modulation. (2018, neutral): “As gut commensals contribute to 189 food digestion, links between diet and the microbiome have been studied for years, at different 190 levels of resolution (reviewed e.g. by Flint et al., 2012; Sonnenburg and Bäckhed, 2016).”
Mother-to-Infant Microbial Transmission from Different Body Sites Shapes the Developing Infant Gut Microbiome (2018, background): “…support many functions in the human body, including the facilitation of nutrient absorption that would otherwise be inaccessible to the host (Flint et al., 2012; Wasielewski et al., 2016), the training and modulation of the immune system (Kau et al., 2011; Thaiss et al., 2016), and…”
The First Microbial Colonizers of the Human Gut: Composition, Activities, and Health Implications of the Infant Gut Microbiota (2017, background): “production is a common feature of most gut microbiota members (453).”
A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility (2016, neutral): “…or imbalances in gut microbial community membership and physiology (‘‘dysbiosis’’) correlate with several negative health outcomes, including pathogen susceptibility, inflammatory bowel disease (IBD), and colon cancer (Cameron and Sperandio, 2015; Flint et al., 2012; McKenney and Pamer, 2015).”