The role of ISAba1 in expression of OXA carbapenemase genes in Acinetobacter baumannii.
By J. Turton, M. E. Ward, N. Woodford, M. Kaufmann, R. Pike, D. Livermore, T. Pitt. FEMS Microbiology Letters, 2006
796 citations recorded by the source corpus.
Subfields: Endocrinology, Molecular Biology, Molecular Medicine
View Paper: https://www.semanticscholar.org/paper/dbdca4f95666bff89a982d5cf11c0f8c3abb1259
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Endocrinology
In Molecular Biology
In Molecular Medicine
Citations in the corpus
- Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options (2017, background): “Insertion of ISAba1 in the blaOXA-23 promoter sequence has been reported to be associated with overexpression of blaOXA-23, blaOXA-51, or blaOXA-58 in A. baumannii (Turton et al., 2006a).”
- Updated Functional Classification of β-Lactamases (2009, background): “The 2df enzymes have been divided into nine clusters according to amino acid homologies (52, 59, 62, 66).”
- Acinetobacter baumannii: Emergence of a Successful Pathogen (2008, background): “Most recently, disruption of the adeS gene by the IS element ISAba1 was identified (469).”
- Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp. (2006, background): “Isolates belonging to the third group, the SE clone, show variable carbapenem resistance [4], contingent on the activation or not of blaOXA-51-like by insertion sequences [6].”
- Carbapenemases: the Versatile β-Lactamases (2007, background): “baumannii, insertion sequences of the ISAba1 type, carrying strong promoters, have been detected upstream of the chromosomal oxacillinase, resulting in increased expression and concomitant carbapenemase resistance (212).”
- Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: Mechanisms and epidemiology. (2015, background): “However, once overexpressed they may subsequently be involved in reduced susceptibility to carbapenems [234].”
- Mobile Genetic Elements Associated with Antimicrobial Resistance (2018, neutral): “baumannii giving carbapenem resistance [13]).”
- Identification of Acinetobacter baumannii by Detection of the blaOXA-51-like Carbapenemase Gene Intrinsic to This Species (2006, background): “A further potential problem is that these genes are sometimes associated with ISAba1 (11), which may render them mobile.”