A uniform system for microRNA annotation.

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MicroRNA biogenesis: coordinated cropping and dicing (2005, background): “jpg" NDATA ITEM> ]> MicroRNAs (miRNAs) are single-stranded RNAs (ssRNAs) of 19–25 nucleotides in length that are generated from endogenous hairpin-shaped transcript”
MicroRNAs and other tiny endogenous RNAs in C. elegans. (2003, methodology): “miRNA genes are named according to established conventions [ 36 ]; all miRNAs were confirmed by Northern blot hybridization.”
High expression of precursor microRNA‐155/BIC RNA in children with Burkitt lymphoma (2004, background): “…and trigger either translation repression or direct RNA cleavage via RNA interference, depending on the degree of complementarity with the specific target mRNA (Ambros, 2001; Lagos-Quintana et al., 2001; Ruvkun, 2001; Lai, 2002; Pasquinelli, 2002; Ambros et al., 2003; Lagos-Quintana et al., 2003).”
The microRNAs of Caenorhabditis elegans. (2003, background): “The median score of the 58 previously reported miRNA loci that satisfy the current criteria for designation as miRNA genes (Ambros et al. 2003) is 13.9 (green arrow).”
Prediction and validation of microRNAs and their targets (2005, neutral): “Initially, most microRNAs were discovered by massive cloning and sequencing efforts [10–14], with informatics playing a limited role of verifying that the cloned sequences are part of a hairpin structure, typical of microRNA precursors [ 15 ] .I t was apparent however, that these approaches are limi”