High expression of precursor microRNA‐155/BIC RNA in children with Burkitt lymphoma

By M. Metzler, M. Wilda, Kerstin Busch, S. Viehmann, Arndt Borkhardt. Genes, Chromosomes and Cancer, 2004

605 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/b70440a4797ea12e6bab4148799f9a04b67cfc6f

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Citations in the corpus

Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. (2006, background): “…cancers (Michael et al., 2003) and let-7 in lung cancers (Takamizawa et al., 2004), high expression of the precursor mir-155 in Burkitt’s lymphomas (Metzler et al., 2004), and oncogenic function of mir-17-92 cluster in human B cell lymphomas as well as in lung cancers (He et al., 2005; Hayashita…”
MicroRNAs in cell proliferation, cell death, and tumorigenesis (2006, background): “Flies harbouring a deletion of this miRNA were found to have an increased expression of an apoptotic effector caspase, Drice, which has a putative miR-14 target site (Xu et al, 2003).”
microRNA-155 Regulates the Generation of Immunoglobulin Class-Switched Plasma Cells (2007, background): “…high expression of BIC and miR-155 has been shown in Hodgkin’s lymphoma, primary mediastinal B-cell lymphoma and diffuse large B-cell lymphoma, while very low expression of BIC and miR-155 were reported in adult Burkitt lymphoma (Eis et al., 2005; Metzler et al., 2004; van den Berg et al., 2003).”
MicroRNAs in cancer: small molecules with a huge impact. (2009, positive): “Early studies have shown that miR-155 is upregulated in a subgroup of Burkitt’s lymphoma, diffuse large B-cell lymphoma, primary mediastinal B-cell lymphoma, and Hodgkin’s lymphoma.(9,10) This microRNA is encoded by the terminal portion of the BIC (B-cell integration cluster) gene, which was origina”
microRNAs as oncogenes and tumor suppressors. (2007, background): “Activation of the BIC gene accelerates the pathogenesis of lymphomas and leukemias, and the expression of BIC is elevated in Hodgkin and children's Burkitt lymphoma but is low in normal lymphoid tissues (Haasch et al., 2002; Metzler et al., 2004; van den Berg et al., 2003).”
Suppression of non-small cell lung tumor development by the let-7 microRNA family (2008, background): “The BIC transcript, which was isolated from a common retroviral insertion site that cooperates with c-Myc in lymphomagenesis and is highly up-regulated in Burkitt’s lymphoma, encodes a primary miRNA transcript for miR-155 (8).”
Human MicroRNA Targets (2004, background): “Similarly, miR-143 and miR-145 are down-regulated at the adenomatous and cancer stages of colorectal neoplasia (Michael et al. 2003), and miR-155 is up-regulated in children with Burkitt lymphoma (Metzler et al. 2004).”