Revitalizing membrane rafts: new tools and insights

By K. Simons, M. Gerl. Nature reviews. Molecular cell biology, 2010

1,225 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/daed826ab0de0430fc65edc19c56b987f2428ba4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. G. Nicolson
2. J. Sampaio
3. P. Calder
4. K. Simons
5. C. Dart

In Molecular Biology

1. G. Nicolson
2. J. Sampaio
3. P. Calder
4. A. Schulze
5. K. Simons
6. C. Dart
7. M. Gerl

Citations in the corpus

• Membrane organization and lipid rafts. (2011, background): “Studies in yeast and epithelial Madin– Darby canine kidney (MDCK) cells show that there are pathways from the trans-Golgi, distinct from the well-described coat-mediated routes, which show the capacity to sort membrane lipids.”
• Substrate Effects on the Formation Process, Structure and Physicochemical Properties of Supported Lipid Bilayers (2012, neutral): “microdomains and clusters is emphasized in the concept of the raft [1,2,146].”
• The Fluid-Mosaic Model of Membrane Structure: still relevant to understanding the structure, function and dynamics of biological membranes after more than 40 years. (2014, background): “In addition to the possibility that integral membrane proteins may be sequestered into lipid rafts [206,207,210,212], lipid-linked peripheral proteins can also be caught up in lipid domains [223].”
• Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development (2013, background): “These specialised structures are involved in membrane trafficking and act as essential platforms for the assembly of signalling complexes on the plasma membrane (Simons and Gerl, 2010).”
• Functional Roles of Fatty Acids and Their Effects on Human Health. (2015, background): “cell signaling platforms, are usually rich in saturated fatty acid–containing phospholipids and sphingolipids.(1) Myristic and palmitic acids can covalently modify a number of proteins involved in cell signaling; the fatty acylation is important in anchoring those proteins to the inner leaflet of th”