New roles for astrocytes: redefining the functional architecture of the brain.

By Maiken Nedergaard, B. Ransom, S. Goldman. Trends in Neurosciences, 2003

1,371 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/d8c776b69277f15f1e4533a77e4e5c7ae079314a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. M. Sofroniew
2. M. Pekny
3. M. Pekna
4. Igor Allaman
5. G. Dienel
6. Giorgio Carmignoto
7. M. Hanani
8. Y. Ao

In Developmental Neuroscience

1. M. Sofroniew
2. M. Pekny
3. M. Pekna
4. Y. Ao
5. B. Song
6. M. Hanani
7. H. Vinters
8. Giorgio Carmignoto

In Neurology

1. M. Sofroniew
2. M. Pekny
3. M. Pekna
4. Igor Allaman
5. Y. Ao
6. H. Vinters
7. B. Song
8. Pierre J. Magistretti

Citations in the corpus

• STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury (2008, background): “Astrocytes from GFAP-STAT3CKO mice expressed reduced levels of GFAP, and we cannot rule some level of consequent structural changes that might be revealed by more detailed evaluations, for example with single-cell dye filling (Bushong et al., 2002; Nedergaard et al., 2003).”
• Astrocyte control of synaptic transmission and neurovascular coupling. (2006, background): “Although these cells play critical roles in supporting neuronal function, astrocytic Ca(2) excitability and the consequent induced release of chemical transmitters, which we now term gliotransmitters, has led to an emerging new understanding of the functional roles played by these glial cells; we no”
• A cellular perspective on brain energy metabolism and functional imaging. (2015, background): “Indeed, astrocytes feature multiple processes that define spherical volumes of cortex approximately 80–100 mm in diameter (Bushong et al., 2002; Nedergaard et al., 2003; Sofroniew and Vinters, 2010).”
• Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. (2011, background): “Nevertheless, under particular circumstances the brain has the capacity to use other blood-derived energy substrates, such as ketone bodies during development and starvation (Nehlig, 2004; Magistretti, 2008) or lactate during periods of intense physical activity (van Hall et al., 2009).”
• Astrocyte reactivity and reactive astrogliosis: costs and benefits. (2014, background): “As the relative number of astrocytes, expressed as a ratio to neuronal number, increased dramatically during phylogenesis along with the increase in brain complexity (158), it is tempting to speculate that those acute responses of astrocytes allowing survival and some measure of repair, albeit at th”
• Satellite glial cells in sensory ganglia: from form to function. (2005, background): “They control the microenvironment of the brain [65,138] and participate in the regulation of synaptic transmission [67,119,179].”
• LPA receptor signaling: pharmacology, physiology, and pathophysiology (2014, background): “Astrocytes are the most abundant type of glia and play a significant role in developmental, functional, and pathological processes (116).”